Evidence map›Paper›PMID 39158820›Full record

ArticleSpine deformity2025

Associations of overweight status with spinal curve correction and complications in patients undergoing vertebral body tethering: a multicenter retrospective review.

William ElNemer, Daniel Badin, Shyam J Kurian, Stefan Parent, Firoz Miyanji, Daniel Hoernschemeyer, Ahmet Alanay, Harms Study Group, Paul D Sponseller

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Spine deformity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

William ElNemerDepartment of Orthopaedic Surgery, The Johns Hopkins University, 601 N Caroline St., Baltimore, MD, 21287, USA.
Daniel BadinDepartment of Orthopaedic Surgery, The Johns Hopkins University, 601 N Caroline St., Baltimore, MD, 21287, USA.
Shyam J KurianDepartment of Orthopaedic Surgery, The Johns Hopkins University, 601 N Caroline St., Baltimore, MD, 21287, USA.
Stefan ParentDepartment of Orthopaedic Surgery, Sainte-Justine University Hospital, Montreal, QC, Canada.
Firoz MiyanjiDepartment of Orthopaedic Surgery, University of British Columbia, Vancouver, BC, Canada.
Daniel HoernschemeyerDepartment of Orthopaedic Surgery, University of Missouri-Columbia, Columbia, MO, USA.
Ahmet AlanayDepartment of Orthopedics and Traumatology, Acıbadem University School of Medicine, Istanbul, Turkey.
Harms Study Group
Paul D SponsellerDepartment of Orthopaedic Surgery, The Johns Hopkins University, 601 N Caroline St., Baltimore, MD, 21287, USA. psponse1@jh.edu.ORCID http://orcid.org/0000-0003-2934-6374

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeOur purpose was to determine associations between body mass index (BMI) category and outcomes of vertebral body tethering (VBT), a non-fusion treatment for adolescent idiopathic scoliosis (AIS) and juvenile idiopathic scoliosis (JIS).

methodsUsing a multicenter database, we identified patients with AIS or JIS who underwent VBT from 2012 to 2018 and had minimum 2-year follow-up (median, 3.0 [interquartile range 2.2, 3.8]). BMI percentiles were used to classify patients as overweight (≥ 85th percentile) or non-overweight (< 85th percentile). Univariate and multivariate regressions assessed associations between complication rates and curve correction between groups, controlling for sex, triradiate cartilage closure, and preoperative curve magnitude.

resultsOf 271 patients, 48 (18%) were overweight. Complication rates did not differ between groups. Factors associated with less correction from preoperative to first postoperative-erect imaging were overweight (β = - 10, p < 0.001), male sex (β = - 8.8 p < 0.01), closed triradiate cartilage (β = 6.0, p = 0.01), and smaller preoperative curve (β = 0.3, p < 0.01). Factors associated with a larger curve at latest follow-up were overweight (β = 4.0, p = 0.02) and larger preoperative curve (β = 0.5, p < 0.001), but tether breakage did not differ between groups (p = 0.31).

conclusionIn patients who were overweight, VBT was associated with less curve correction at first erect imaging and larger final curve. However, complications and curve correction during the modulation phase were not different from those of non-overweight patients. These findings suggest that surgeons should expect less correction with VBT in patients who are overweight but similar correction over time. LEVEL OF EVIDENCE: Prognostic, Level III.

Indexed as

OverweightPostoperative ComplicationsScoliosisVertebral BodyAdolescentBody Mass IndexChildFemaleHumansMaleRetrospective StudiesTreatment OutcomeAdolescent idiopathic scoliosisBody mass indexCurve correctionJuvenile idiopathic scoliosisVertebral body tethering

Identifiers

PMID39158820

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.