Evidence map›Paper›PMID 39158606›Full record

SynthesisSurgery today2025

Correlation between the C-reactive protein (CRP)-albumin-lymphocyte (CALLY) index and the prognosis of gastric cancer patients after gastrectomy: a systematic review and meta-analysis.

Jinquan Li, Shanzhong Zhang, Xiaosheng Hu, Tao Huang, Mingmin Chen

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Surgery today, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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  16. Prognostic Significance of the CALLY Index in Heart Failure.International journal of general medicine · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jinquan LiDepartment of Gastrointestinal Surgery, The First People's Hospital of Jingdezhen, No. 317 Zhonghuabei Road, Zhushan District, Jingdezhen, 33300, Jiangxi, China.
Shanzhong ZhangDepartment of Gastrointestinal Surgery, The First People's Hospital of Jingdezhen, No. 317 Zhonghuabei Road, Zhushan District, Jingdezhen, 33300, Jiangxi, China. 490982814@qq.com.ORCID http://orcid.org/0009-0004-7477-0267
Xiaosheng HuDepartment of Gastrointestinal Surgery, The First People's Hospital of Jingdezhen, No. 317 Zhonghuabei Road, Zhushan District, Jingdezhen, 33300, Jiangxi, China.
Tao HuangDepartment of Gastrointestinal Surgery, The First People's Hospital of Jingdezhen, No. 317 Zhonghuabei Road, Zhushan District, Jingdezhen, 33300, Jiangxi, China.
Mingmin ChenDepartment of Gastrointestinal Surgery, The First People's Hospital of Jingdezhen, No. 317 Zhonghuabei Road, Zhushan District, Jingdezhen, 33300, Jiangxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The C-Reactive Protein (CRP)-Albumin-Lymphocyte (CALLY) index is an established immuno-nutritional scoring system. We screened relevant literature from the major databases up until May, 2024, and extracted the data for analysis. A total of 2829 gastric cancer (GC) patients from six studies were included in this meta-analysis, the results of which revealed that the CALLY index was an independent prognostic factor for OS and RFS in both univariate analyses and multivariate analyses, and that a high CALLY index was a favorable prognostic factor. Moreover, GC patients in the high CALLY index group seemed to have better 5-year OS and 5-year RFS than those in the low CALLY index group. There was a higher proportion of patients with T1 status in the high CALLY index group than in the low CALLY index group. However, the opposite results were found in the analyses of lymph node metastasis positivity, lymph-vascular invasion positivity, postoperative complications, differentiated histological type, anastomotic leakage, and adjuvant chemotherapy. The present meta-analysis concluded that the CALLY index was a simple and useful independent prognostic biomarker for GC patients after gastrectomy.

Indexed as

Biomarkers, TumorC-Reactive ProteinGastrectomyLymphocytesSerum AlbuminStomach NeoplasmsBiomarkersHumansLymphatic MetastasisLymphocyte CountPostoperative ComplicationsPrognosisBiomarkersBiomarkers, TumorC-Reactive ProteinSerum AlbuminCALLYC-reactive protein(CRP)-albumin-lymphocyte indexGastric cancerMeta-analysisPrognosis

Identifiers

PMID39158606

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.