A genome-scale metabolic model of a globally disseminated hyperinvasive M1 strain of
Yujiro Hirose, Daniel C Zielinski, Saugat Poudel, Kevin Rychel, Jonathon L Baker, Yoshihiro Toya, Masaya Yamaguchi, Almut Heinken, Ines Thiele, Shigetada Kawabata and 2 more
Article in mSystems, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
12 authors.
Yujiro HiroseDepartment of Microbiology, Osaka University Graduate School of Dentistry, Suita, Osaka, Japan.ORCID 0000-0001-6338-4767
Daniel C ZielinskiDepartment of Bioengineering, University of California San Diego, La Jolla, California, USA.
Saugat PoudelDepartment of Bioengineering, University of California San Diego, La Jolla, California, USA.
Kevin RychelDepartment of Bioengineering, University of California San Diego, La Jolla, California, USA.
Jonathon L BakerDepartment of Pediatrics, University of California at San Diego School of Medicine, La Jolla, California, USA.ORCID 0000-0001-5378-322X
Yoshihiro ToyaDepartment of Bioinformatic Engineering, Graduate School of Information Science and Technology, Osaka University, Suita, Osaka, Japan.ORCID 0000-0001-9670-6961
Masaya YamaguchiDepartment of Microbiology, Osaka University Graduate School of Dentistry, Suita, Osaka, Japan.
Almut HeinkenSchool of Medicine, National University of Galway, Galway, Ireland.
Ines ThieleSchool of Medicine, National University of Galway, Galway, Ireland.
Shigetada KawabataDepartment of Microbiology, Osaka University Graduate School of Dentistry, Suita, Osaka, Japan.
Bernhard O PalssonDepartment of Bioengineering, University of California San Diego, La Jolla, California, USA.ORCID 0000-0003-2357-6785
Victor NizetDepartment of Pediatrics, University of California at San Diego School of Medicine, La Jolla, California, USA.ORCID 0000-0003-3847-0422
Funding
Cathelicidin in Skin ImmunityR37AI052453 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Richard L Gallo, Victor Nizet · 2019 to 2026
$4.6M
Identifying the Most Effective Adjuvant(s) for Leading Group A Streptococcal Vaccine Antigens in Preclinical Mouse and Nonhuman Primate ModelsR01AI173689 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Victor Nizet, Mark Joseph Walker · 2023 to 2026
$2.8M
Investigating Membrane Alterations as a Mechanism of Acid Tolerance in Cariogenic BacteriaK99DE029228 · NIDCR · J. CRAIG VENTER INSTITUTE, INC. · PI BAKER, JONATHON · 2020 to 2022
$393k
Fondation Leducq (Leducq Foundation)HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01-AI173689HHS | NIH | National Institute of Dental and Craniofacial Research (NIDCR) K99-DE029228Japan Agency for Medical Research and Development (AMED) JP23wm0325066MEXT | Japan Society for the Promotion of Science (JSPS) 22K09924,22H03262,Overseas Research FellowshipNIAID NIH HHS R01 AI173689NIAID NIH HHS R37 AI052453NIDCR NIH HHS K99 DE029228
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
A genome-scale metabolic model of a globally disseminated hyperinvasive M1 strain of · full record | OpenQuestion