Evidence map›Paper›PMID 39157745›Full record

ArticleInfection and drug resistance2024

Ceftazidime-Avibactam for the Treatment of Central Nervous System Infection Caused by Pan Drug-Resistant Carbapenem-Resistant Klebsiella Pneumoniae: A Case Report.

Yingjie Zhang, Guokuo Hou, Liping Zhang, Shanshan Li

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Infection and drug resistance, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yingjie Zhang *Department of Neurosurgery ICU, The Second Hospital & Clinical Medical School, Lanzhou University, Academician Workstation of The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, 730000, People's Republic of China.ORCID 0000-0003-2520-0554
Guokuo Hou *Department of Neurosurgery ICU, The Second Hospital & Clinical Medical School, Lanzhou University, Academician Workstation of The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, 730000, People's Republic of China.
Liping ZhangDepartment of Neurosurgery ICU, The Second Hospital & Clinical Medical School, Lanzhou University, Academician Workstation of The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, 730000, People's Republic of China.
Shanshan LiDepartment of Neurosurgery ICU, The Second Hospital & Clinical Medical School, Lanzhou University, Academician Workstation of The Second Hospital & Clinical Medical School, Lanzhou University, Lanzhou, 730000, People's Republic of China.ORCID 0009-0000-1798-3021

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Central Nervous System (CNS) infections caused by Carbapenem-resistant Case Presentation: A 46-year-old woman with a 1-day history of post-traumatic disturbance of consciousness and cerebrospinal fluid (CSF) rhinorrhea was referred to our hospital. She underwent external ventricular drainage and decompressive craniectomy, and had a persistent fever. A CSF test confirmed intracranial infection. The minimum inhibitory concentration of polymyxin in this patient was 16 μg/mL. She was diagnosed with polymyxin-resistant pan drug-resistant (PDR) Conclusion: CAZ/AVI combined with polymyxin B may be an effective salvage treatment for CNS infections caused by polymyxin-resistant PDR-KP.

Indexed as

Carbapenem-resistant Klebsiella pneumoniaeceftazidime/avibactamCNS infectionpolymyxin-resistant

Identifiers

PMID39157745
PMCPMC11328857

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.