Evidence map›Paper›PMID 39157620›Full record

ArticleEJHaem2024

Extramedullary chronic phase chronic myeloid leukaemia (CML) involving the central nervous system: A case report.

Akshay Deshpande, Dina Osman, Vidhya Murthy, Hayder Hussein

Abstract readCase Reports
In one paragraph

Article in EJHaem, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Akshay DeshpandeDepartment of Haematology University Hospitals Birmingham NHSFT Birmingham UK.ORCID https://orcid.org/0000-0002-5096-3839
Dina OsmanDepartment of Haematology University Hospitals Birmingham NHSFT Birmingham UK.ORCID https://orcid.org/0000-0002-3668-0250
Vidhya MurthyDepartment of Haematology University Hospitals Birmingham NHSFT Birmingham UK.
Hayder HusseinDepartment of Haematology University Hospitals Birmingham NHSFT Birmingham UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic myeloid leukaemia (CML) has been classically described as a disease restricted to the bone marrow with very few reports of extramedullary involvement. CNS involvement with CML has been described in the literature as an aggressive disease in the leukaemic phase either preceding or coexisting with medullary blast crisis or seen in patients with long-term Imatinib therapy. No treatment consensus exists for this patient group and outcomes remain poor. We hereby present a very rare report of CNS involvement with chronic phase CML at diagnosis in a patient who presented with raised intracranial pressure and cranial nerve palsies.

Indexed as

chronic phaseCMLCNS infiltration

Identifiers

PMID39157620
PMCPMC11327750

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.