Evidence map›Paper›PMID 39157598›Full record

ArticleEJHaem2024

Desmopressin for prevention of bleeding for thrombocytopenic, critically ill patients undergoing invasive procedures: A randomised, double-blind, placebo-controlled feasibility trial.

Michael J R Desborough, Emma Laing, Daphne Kounali, Ana Mora, Renate Hodge, Siobhan Martin, Helen Thomas, Cara Hudson, Joseph Parsons, Akshay Shah and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EJHaem, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Michael J R DesboroughDepartment of Clinical Haematology Oxford University Hospitals NHS Foundation Trust Oxford UK.ORCID https://orcid.org/0000-0002-1951-5616
Emma LaingNHS Blood and Transplant Clinical Trials Unit Cambridge UK.
Daphne KounaliNHS Blood and Transplant Clinical Trials Unit Bristol UK.
Ana MoraNHS Blood and Transplant Clinical Trials Unit Cambridge UK.
Renate HodgeNHS Blood and Transplant Clinical Trials Unit Cambridge UK.
Siobhan MartinNHS Blood and Transplant Clinical Trials Unit Cambridge UK.
Helen ThomasNHS Blood and Transplant Clinical Trials Unit Bristol UK.
Cara HudsonNHS Blood and Transplant Clinical Trials Unit Bristol UK.
Joseph ParsonsNHS Blood and Transplant Clinical Trials Unit Bristol UK.
Akshay ShahDepartment of Critical Care Oxford University Hospitals NHS Foundation Trust Oxford UK.
Paula HuttonDepartment of Critical Care Oxford University Hospitals NHS Foundation Trust Oxford UK.
Tim ParkeDepartment of Critical Care Royal Berkshire Hospital Reading UK.
Matthew P WiseDepartment of Critical Care University Hospital of Wales Cardiff UK.
Matthew MorganDepartment of Critical Care University Hospital of Wales Cardiff UK.
Stuart McKechnieDepartment of Critical Care Oxford University Hospitals NHS Foundation Trust Oxford UK.
Simon J StanworthDepartment of Clinical Haematology Oxford University Hospitals NHS Foundation Trust Oxford UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thrombocytopenic patients have an increased risk of bleeding when undergoing invasive procedures. In a multicentre, phase II, blinded, randomised, controlled feasibility trial, critically ill patients with platelet count 100 × 10

Indexed as

bleeding disordersdesmopressinthrombocytopenia

Identifiers

PMID39157598
PMCPMC11327725

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.