Evidence map›Paper›PMID 39157595›Full record

ArticleEJHaem2024

Effective treatment of refractory monoclonal gammopathy-associated pure red cell aplasia with isatuximab, pomalidomide and dexamethasone.

Christian Sebastian Michel, Eva Marie Fehr, Hildegard Nolte, Joachim Beck, Andreas Kreft, Katharina Theresa Rauschkolb-Olk, Bjoern Jacobi, Matthias Theobald, Markus Munder

Abstract readCase Reports
In one paragraph

Article in EJHaem, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Christian Sebastian MichelDepartment of Hematology and Medical Oncology University Medical Center of the Johannes Gutenberg University Mainz Germany.ORCID https://orcid.org/0009-0004-1596-3763
Eva Marie FehrDepartment of Hematology and Medical Oncology University Medical Center of the Johannes Gutenberg University Mainz Germany.
Hildegard NolteDepartment of Hematology and Medical Oncology University Medical Center of the Johannes Gutenberg University Mainz Germany.
Joachim BeckDepartment of Hematology and Medical Oncology University Medical Center of the Johannes Gutenberg University Mainz Germany.
Andreas KreftDepartment of Pathology University Medical Center of the Johannes Gutenberg University Mainz Germany.
Katharina Theresa Rauschkolb-OlkInstitute of Clinical Chemistry and Laboratory Medicine University Medical Center of the Johannes Gutenberg University Mainz Germany.
Bjoern JacobiDepartment of Hematology and Medical Oncology University Medical Center of the Johannes Gutenberg University Mainz Germany.
Matthias TheobaldDepartment of Hematology and Medical Oncology University Medical Center of the Johannes Gutenberg University Mainz Germany.
Markus MunderDepartment of Hematology and Medical Oncology University Medical Center of the Johannes Gutenberg University Mainz Germany.ORCID https://orcid.org/0000-0003-4947-8796

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monoclonal gammopathy-associated pure red cell aplasia (MG-PRCA) is characterized by the absence or pronounced hypoplasia of erythroid precursors in the bone marrow, causing reticulocytopenia and a normocytic, normochromic anaemia in a patient with a monoclonal plasma cell dyscrasia. We report here on the successful treatment of MG-PRCA with isatuximab, pomalidomide, and dexamethasone after multiple lines of immunosuppressive and anti-plasma cell-directed treatments.

Indexed as

MGUSmultiple myelomapure red cell aplasia

Identifiers

PMID39157595
PMCPMC11327726

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.