Evidence map›Paper›PMID 39157436›Full record

ArticleJournal of chemical education2024

Building a Simplistic Automatic Extruder: Instrument Development Opportunities for the Laboratory.

Stefanie Klisch, Dylan Gilbert, Emma Breaux, Aliyah Dalier, Sudipta Gupta, Bruno Jakobi, Gerald J Schneider

Abstract read
In one paragraph

Article in Journal of chemical education, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Stefanie KlischDepartment of Chemistry, Louisiana State University, Baton Rouge, Louisiana 70803, United States.ORCID https://orcid.org/0009-0002-1467-9387
Dylan GilbertDepartment of Chemistry and Physics Southeastern Louisiana University, Hammond, Louisiana 70402, United States.
Emma BreauxDepartment of Chemistry, Louisiana State University, Baton Rouge, Louisiana 70803, United States.
Aliyah DalierDepartment of Chemistry and Physics Southeastern Louisiana University, Hammond, Louisiana 70402, United States.
Sudipta GuptaDepartment of Chemistry, Louisiana State University, Baton Rouge, Louisiana 70803, United States.ORCID https://orcid.org/0000-0001-6642-3776
Bruno JakobiDepartment of Chemistry, Louisiana State University, Baton Rouge, Louisiana 70803, United States.ORCID https://orcid.org/0000-0003-1171-9486
Gerald J SchneiderDepartment of Chemistry, Louisiana State University, Baton Rouge, Louisiana 70803, United States.ORCID https://orcid.org/0000-0002-5577-9328

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This work presents an automatic extruder as a research experience for undergraduate students. The system offers a user-friendly approach to preparing vesicles, such as liposomes or polymersomes, with a defined size and polydispersity-properties crucial for research in biology and macromolecules. It comprises two syringe pumps connected by a membrane filter. The setup is controlled by software. Compared to manual extrusion, this automated system provides advantages, such as precisely controlled variables. The project describes a tool to enhance undergraduate learning in science and engineering laboratories. Building an automatic extruder serves as a simplified model of a complex industrial process. It offers a clear advantage: automating a well-understood manual extrusion process. To make this project accessible, it is broken down into three manageable tasks: software development, hardware assembly, and testing procedures. This breakdown describes the software created, the hardware components used, and the testing procedures conducted for this project. All project data, including software code, testing data, and procedures, are freely available online. This allows undergraduate students to not only begin their own projects but also contribute to this educational instrument's ongoing development.

Identifiers

PMID39157436
PMCPMC11327960

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.