Evidence map›Paper›PMID 39157206›Full record

ReviewFrontiers in oral health2024

Recent advances in minimally invasive biomarkers of OSCC: from generalized to personalized approach.

Smriti Suri, Geeta S Boora, Rajandeep Kaur, Anshika Chauhan, Sushmita Ghoshal, Arnab Pal

Abstract readReview
In one paragraph

Review in Frontiers in oral health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
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  8. In Silico Analysis of Squamous Cell Carcinoma.Advances in experimental medicine and biology · 2026
    Review
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  19. Immunoprofile of some transmembrane adhesion molecules in oral squamous cell carcinoma.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Smriti SuriDepartment of Biochemistry, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Geeta S BooraDepartment of Biochemistry, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Rajandeep KaurDepartment of Biochemistry, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Anshika ChauhanDepartment of Biochemistry, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Sushmita GhoshalDepartment of Radiotherapy, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Arnab PalDepartment of Biochemistry, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral cancer is the 6th most common type of cancer worldwide, and oral squamous cell carcinoma (OSCC) accounts for >90% of oral cancers. It is a major health problem, particularly in low- and middle-income countries (LMICs), due to both its high incidence and significant mortality and morbidity. Despite being a global burden, and even with the significant advancement in the management of OSCC, the overall outcome of the disease is still abysmal. With the advent of time, advanced diagnostic and treatment approaches have come into practice, but the burden of the disease has not improved significantly. Major reasons attributed to the poor outcome are delay in diagnosis, locoregional recurrence and resistance to the currently available treatment regimen. In this review, we have highlighted the existing challenges in the diagnosis and have emphasized the advancements in minimally invasive biomarkers. Additionally, the importance of collaborative multidimensional approaches involving clinicians and researchers has been discussed, as well as the need to redefine and establish better utility and management of existing diagnostic and treatment protocols along with the minimally invasive/non-invasive biomarkers.

Indexed as

circulating tumour cell (CTC)circulating tumour DNA (ctDNA)genomic biomarkersminimally invasive biomarkeroral squamous cell carcinoma (OSCC)proteomic biomarker

Identifiers

PMID39157206
PMCPMC11327221

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.