Evidence map›Paper›PMID 39156916›Full record

ReviewInternational journal of cardiology. Heart & vasculature2024

Association between inflammatory bowel disease and atrial fibrillation: A systematic review and

Aman Goyal, Hritvik Jain, Surabhi Maheshwari, Jyoti Jain, Ramez M Odat, Humza Saeed, Mohamed Daoud, Gauranga Mahalwar, Kamna Bansal

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of cardiology. Heart & vasculature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Inflammation and day-to-day occurrence of atrial fibrillation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Aman GoyalDepartment of Internal Medicine, Seth GS Medical College and KEM Hospital, Mumbai, India.
Hritvik JainDepartment of Internal Medicine, All India Institute of Medical Sciences (AIIMS), Jodhpur, India.
Surabhi MaheshwariDepartment of Internal Medicine, University of Alabama, Montgomery, AL, USA.
Jyoti JainDepartment of Internal Medicine, All India Institute of Medical Sciences (AIIMS), Jodhpur, India.
Ramez M OdatFaculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
Humza SaeedDepartment of Internal Medicine, Rawalpindi Medical University (RMU), Rawalpindi, Pakistan.
Mohamed DaoudBogomolets National Medical University, Kyiv, Ukraine.
Gauranga MahalwarDepartment of Internal Medicine, Cleveland Clinic Foundation, Cleveland, OH, USA.
Kamna BansalDepartment of Family and Community Medicine, Baylor College of Medicine, Houston, TX, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Inflammatory bowel disease (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), is a prevalent condition associated with chronic noninfectious inflammation of the gastrointestinal tract. It has been hypothesized that chronic inflammation can predispose patients to atrial fibrillation (AF), however, no clear evidence exists to support this. Methods: A systematic literature search was conducted using major databases aimed at studies focusing on AF development in patients with IBD. Further subgroup analyses were performed for ulcerative colitis (UC) and crohn's disease (CD). Risk ratios (RR) with their corresponding 95 % confidence intervals (CI) were pooled using a random-effects model in the Review Manager Software. Statistical significance was set at p < 0.05. Results: Seven studies with 88,893,407 patients were included (1,002,719 and 87, 890, 688 patients in the IBD and non-IBD groups, respectively). IBD patients were at an increased risk of developing AF [RR: 1.52; 95 % CI: 1.19-1.95; p = 0.0009] compared to the non-IBD group. In subgroup analyses, patients with UC were at an increased risk of developing AF [RR: 1.29; 95 % CI: 1.08-1.53; p = 0.004], as were CD patients [RR: 1.30; 95 % CI: 1.07-1.58; p = 0.008] compared to the non-UC and non-CD groups, respectively. Conclusion: Patients with IBD are at nearly 1.5 times the risk of developing AF compared to the non-IBD population. Our

Indexed as

Atrial fibrillationInflammatory bowel diseaseMeta-analysisRisk

Identifiers

PMID39156916
PMCPMC11327605

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.