Evidence map›Paper›PMID 39156853›Full record

ArticleIndian journal of nephrology

Podocyte Infolding Glomerulopathy Masquerading as Membranous Nephropathy - A Shared Pathogenesis?

Smita Mary Matthai, Liam Hems, Yee Wah Tsang, Yogita Aggarwal, Huda Mahmoud, Kishore Gopalakrishnan

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PubMed Full text at PMC Publisher
In one paragraph

Article in Indian journal of nephrology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Smita Mary MatthaiCentral EM Facility, Christian Medical College, Vellore, Tamil Nadu, India.
Liam HemsDepartment of Cellular Pathology, University Hospital Coventry and Warwickshire, Coventry, UK.
Yee Wah TsangDepartment of Cellular Pathology, University Hospital Coventry and Warwickshire, Coventry, UK.
Yogita AggarwalDepartment of Renal Medicine, University Hospital Coventry and Warwickshire, Coventry, UK.
Huda MahmoudDepartment of Nephrology, Walsall Manor Hospital, Walsall, UK.
Kishore GopalakrishnanDepartment of Cellular Pathology, University Hospital Coventry and Warwickshire, Coventry, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Podocyte infolding glomerulopathy (PIG) is a rare pathological entity, diagnosed by electron microscopic demonstration of diffuse infolding of the podocytes into the glomerular basement membranes. We report the first case from United Kingdom exhibiting typical ultrastructural features of PIG in a male with Type II diabetes mellitus, hypertension and common variable immune deficiency. Renal biopsy revealed phospholipase A2 receptor (PLA2R) immunostain positive membranous nephropathy (MN) but no serum PLA2R antibodies. Diffuse infolding of the podocytes into the glomerular basement membranes along with pathognomonic microspherular and microtubular intra basement membrane clusters distributed diffusely and globally were noted on electron microscopy, diagnostic of PIG. We postulate a shared pathomechanistic link between PIG and MN, highlighting the overlapping features of both conditions.

Indexed as

Electron microscopyMembranous nephropathyPhospholipase A2 receptorPodocyte infolding glomerulopathyPodocytopathy

Identifiers

PMID39156853
PMCPMC11326786

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Registered trials

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