Evidence map›Paper›PMID 39156645›Full record

ArticleiScience2024

Monitoring GPCR conformation with GFP-inspired dyes.

Anatoliy Belousov, Ivan Maslov, Philipp Orekhov, Polina Khorn, Pavel Kuzmichev, Nadezhda Baleeva, Vladislav Motov, Andrey Bogorodskiy, Svetlana Krasnova, Konstantin Mineev and 12 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Anatoliy BelousovMoscow Institute of Physics and Technology, Dolgoprudny 141701, Russia.
Ivan MaslovMoscow Institute of Physics and Technology, Dolgoprudny 141701, Russia.
Philipp OrekhovFaculty of Biology, Shenzhen MSU-BIT University, Shenzhen 518172, China.
Polina KhornMoscow Institute of Physics and Technology, Dolgoprudny 141701, Russia.
Pavel KuzmichevMoscow Institute of Physics and Technology, Dolgoprudny 141701, Russia.
Nadezhda BaleevaInstitute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997, Russia.
Vladislav MotovMoscow Institute of Physics and Technology, Dolgoprudny 141701, Russia.
Andrey BogorodskiyMoscow Institute of Physics and Technology, Dolgoprudny 141701, Russia.
Svetlana KrasnovaInstitute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997, Russia.
Konstantin MineevMoscow Institute of Physics and Technology, Dolgoprudny 141701, Russia.
Dmitry ZinchenkoBranch of Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Pushchino 142290, Russia.
Evgeni ZerniiBelozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, Moscow 119992, Russia.
Valentin IvanovichMoscow Institute of Physics and Technology, Dolgoprudny 141701, Russia.
Sergei PermyakovInstitute for Biological Instrumentation, Russian Academy of Sciences, Pushchino 142292, Russia.
Johan HofkensLaboratory for Photochemistry and Spectroscopy, Division for Molecular Imaging and Photonics, Department of Chemistry, KU Leuven, 3001 Leuven, Belgium.
Jelle HendrixDynamic Bioimaging Lab, Advanced Optical Microscopy Centre, Biomedical Research Institute, Agoralaan C (BIOMED), Hasselt University, 3590 Diepenbeek, Belgium.
Vadim CherezovDepartment of Chemistry, University of Southern California, Los Angeles, CA 90089, USA.
Thomas GenschLaboratory for Photochemistry and Spectroscopy, Division for Molecular Imaging and Photonics, Department of Chemistry, KU Leuven, 3001 Leuven, Belgium.
Alexander MishinInstitute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997, Russia.
Mikhail BaranovInstitute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow 117997, Russia.
Alexey MishinMoscow Institute of Physics and Technology, Dolgoprudny 141701, Russia.
Valentin BorshchevskiyMoscow Institute of Physics and Technology, Dolgoprudny 141701, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Solvatochromic compounds have emerged as valuable environment-sensitive probes for biological research. Here we used thiol-reactive solvatochromic analogs of the green fluorescent protein (GFP) chromophore to track conformational changes in two proteins, recoverin and the A

Indexed as

BiochemistryBiophysicsStructural biology

Identifiers

PMID39156645
PMCPMC11326922

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.