Evidence map›Paper›PMID 39156636›Full record

ReviewiScience2024

Mining human clinical waste as a rich source of stem cells for neural regeneration.

Zahra Eivazi Zadeh, Shirin Nour, Sogol Kianersi, Farinaz Jonidi Shariatzadeh, Richard J Williams, David R Nisbet, Kiara F Bruggeman

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in iScience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Melatonin and angiogenesis potential in stem cells.Stem cell research & therapy · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zahra Eivazi ZadehDepartment of Biomedical Engineering, University of Melbourne, Parkville, VIC 3010, Australia.
Shirin NourDepartment of Biomedical Engineering, University of Melbourne, Parkville, VIC 3010, Australia.
Sogol KianersiScience Foundation Ireland (SFI) Centre for Research in Medical Devices (CÚRAM), Biomedical Sciences, University of Galway, Galway, Ireland.
Farinaz Jonidi ShariatzadehBiomedical Engineering, Faculty of Engineering, University of Manitoba, Winnipeg, MB R3T 2N2, Canada.
Richard J WilliamsThe Graeme Clark Institute, University of Melbourne, Melbourne, VIC, Australia.
David R NisbetDepartment of Biomedical Engineering, University of Melbourne, Parkville, VIC 3010, Australia.
Kiara F BruggemanLaboratory of Advanced Biomaterials Research, School of Engineering, Australian National University, Canberra, ACT, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neural diseases are challenging to treat and are regarded as one of the major causes of disability and morbidity in the world. Stem cells can provide a solution, by offering a mechanism to replace damaged circuitry. However, obtaining sufficient cell sources for neural regeneration remains a significant challenge. In recent years, waste-derived stem(-like) cells (WDS-lCs) extracted from both prenatal and adult clinical waste tissues/products, have gained increasing attention for application in neural tissue repair and remodeling. This often-overlooked pool of cells possesses favorable characteristics; including self-renewal, neural differentiation, secretion of neurogenic factors, cost-effectiveness, and low ethical concerns. Here, we offer a perspective regarding the biological properties, extraction protocols, and preclinical and clinical treatments where prenatal and adult WDS-lCs have been utilized for cell replacement therapy in neural applications, and the challenges involved in optimizing these approaches toward patient led therapies.

Indexed as

NeuroscienceStem cells research

Identifiers

PMID39156636
PMCPMC11326931

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.