Evidence map›Paper›PMID 39156502›Full record

ArticleWorld journal of gastroenterology2024

Leech

Xia Liu, Xing-Qiu Liang, Tian-Cai Lu, Zhe Feng, Min Zhang, Nan-Qing Liao, Feng-Lian Zhang, Bo Wang, Li-Sheng Wang

Abstract read
In one paragraph

Article in World journal of gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Freeze-DriedBiomolecules · 2026
    Article
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xia LiuMedical College, Guangxi University, Nanning 530004, Guangxi Zhuang Autonomous Region, China.
Xing-Qiu LiangDepartment of Science and Technology, Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning 530011, Guangxi Zhuang Autonomous Region, China.
Tian-Cai LuGeneral Manager's Office, Guangxi Fuxinyi Biological Technology Co. Ltd., Pingnan 537300, Guangxi Zhuang Autonomous Region, China.
Zhe FengDepartment of Joint and Sports Medicine, Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning 530011, Guangxi Zhuang Autonomous Region, China.
Min ZhangDepartment of Gerontology, Nanning Social Welfare Hospital, Nanning 530004, Guangxi Zhuang Autonomous Region, China.
Nan-Qing LiaoMedical College, Guangxi University, Nanning 530004, Guangxi Zhuang Autonomous Region, China.
Feng-Lian ZhangMedical College, Guangxi University, Nanning 530004, Guangxi Zhuang Autonomous Region, China.
Bo WangMedical College, Guangxi University, Nanning 530004, Guangxi Zhuang Autonomous Region, China.
Li-Sheng WangMedical College, Guangxi University, Nanning 530004, Guangxi Zhuang Autonomous Region, China. lswang@gxu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHyperuricemia (HUA) is a public health concern that needs to be solved urgently. The lyophilized powder of

aimTo explore the underlying mechanisms of

methodsA mouse model of rapid HUA was established using a high-purine diet and potassium oxonate injections. The mice received oral drugs or saline. Additionally, 16S rRNA sequencing and ultra-high performance liquid chromatography with quadrupole time-of-flight mass spectrometry-based untargeted metabolomics were performed to identify changes in the microbiome and host metabolome, respectively. The levels of uric acid transporters and epithelial tight junction proteins in the renal and intestinal tissues were analyzed using an enzyme-linked immunosorbent assay.

resultsThe protein extract of

conclusionThe proteins in

Indexed as

Disease Models, AnimalGastrointestinal MicrobiomeHyperuricemiaLeechesAnimalsDysbiosisHumansKidneyMaleMetabolomeMetabolomicsMiceRNA, Ribosomal, 16SUric AcidRNA, Ribosomal, 16SUric AcidGalactose metabolism pathwayGut microbiotaHyperuricemiaMetabolismMulti-omicsPoecilobdella manillensisSphingolipid metabolism pathway

Identifiers

PMID39156502
PMCPMC11326090

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.