Evidence map›Paper›PMID 39156389›Full record

ArticleCureus2024

Non-syndromic Cleft Lip and Palate Patients of the North Indian Population and the Association of Methylenetetrahydrofolate Reductase Gene.

Juhi Yadav, Pradeep Raghav, Raj Kumar Mishra, Divya Narain Upadhyaya, Veerendra Prasad, Chandra P Chaturvedi, Kritanjali Singh

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Juhi YadavDepartment of Orthodontics and Dentofacial Orthopedics, Autonomous State Medical College, Auraiya, Auraiya, IND.
Pradeep RaghavDepartment of Orthodontics, Swami Vivekanand Subharti University, Meerut, IND.
Raj Kumar MishraDepartment of Plastic Surgery and Reconstructive Surgery, Sushrut Institute of Plastic Surgery, Lucknow, IND.
Divya Narain UpadhyayaDepartment of Plastic Surgery and Reconstructive Surgery, King George's Medical University, Lucknow, IND.
Veerendra PrasadDepartment of Plastic Surgery, King George's Medical University, Lucknow, IND.
Chandra P ChaturvediStem Cell Research Center, Department of Hematology, Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS), Lucknow, IND.
Kritanjali SinghDepartment of Biotechnology, Swami Vivekanand Subharti University, Meerut, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCleft lip and palate (CLP) is a common congenital anomaly characterized by incomplete fusion of the lip and/or palate during embryonic development. The etiology of CLP is multifactorial, involving genetics and different environmental factors. The methylenetetrahydrofolate reductase ( AIM AND

objectivesThis research aimed to see the association between MATERIALS AND

methodA case-control observational design comprised 50 CLP patients (cases) and 50 healthy individuals without CLP (controls). Blood samples were collected from patients visiting two hospitals. Genomic DNA was extracted from collected peripheral blood samples, and the genotyping of

resultThis research revealed a significant association between

conclusionThis study provides evidence for a linkage between the

Indexed as

cleft lip and palategenetic polymorphismsmthfr genenon-syndromic patientsnorth indian population

Identifiers

PMID39156389
PMCPMC11330085

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.