Evidence map›Paper›PMID 39156375›Full record

ArticleCureus2024

Ethambutol-Induced Optic Neuritis and Vision Loss: A Case Report.

Jaykumar Patel, Chetna Patel, Akash Shah, Paras Shah, Sajal Pandya, Brijesh Sojitra

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jaykumar PatelPharmacology, Government Medical College, Surat, Surat, IND.
Chetna PatelPharmacology, Government Medical College and New Civil Hospital, Surat, Surat, IND.
Akash ShahPharmacology and Therapeutics, Government Medical College, Surat, Surat, IND.
Paras ShahPharmacology, Government Medical College, Surat, Surat, IND.
Sajal PandyaPharmacology, Government Medical College Surat, Surat, IND.
Brijesh SojitraPharmacology and Therapeutics, Government Medical College, Surat, Surat, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ethambutol is a first-line chemotherapeutic agent, which is commonly used in combination with other drugs for the treatment of tuberculosis. Ethambutol-induced optic neuritis is a serious and rare side effect that is either dose or duration-related and causes progressive painless vision loss, and cecocentral scotomas in the visual field. A rare case of ethambutol-induced optic neuritis was reported in a 52-year-old female who was taking anti-tubercular treatment for pulmonary tuberculosis for five months. She presented with painless diminished vision in both eyes. The patient was diagnosed with a rare case of optic neuritis through various examination methods. Ethambutol was stopped and therapy was continued with oral prednisone, zinc, and vitamin B complex being started along with anti-TB treatment. She showed no marked improvement in visual parameters until the last follow-up. The patient died due to cardiopulmonary arrest as a consequence of pulmonary tuberculosis.

Indexed as

anti-tubercular treatmentethambutoloptic neuritisside effectvision loss

Identifiers

PMID39156375
PMCPMC11330547

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.