Evidence map›Paper›PMID 39156153›Full record

ArticleKidney international reports2024

Elevated Exposure to Air Pollutants Accelerates Primary Glomerular Disease Progression.

Jonathan P Troost, Jennifer D'Souza, Miatta Buxton, Abhijit V Kshirsagar, Lawrence S Engel, Cassandra R O'Lenick, William E Smoyer, Jon Klein, Wenjun Ju, Sean Eddy and 4 more

Abstract read
In one paragraph

Article in Kidney international reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Atmospheric stressors and kidney diseases.Nature reviews. Nephrology · 2026
    Review
  2. Review
  3. Article
  4. Chronic PMScientific reports · 2026
    Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Long-term effects of PMBMC public health · 2025
    Article
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Jonathan P TroostMichigan Institute for Clinical & Health Research, University of Michigan, Ann Arbor Michigan, USA.
Jennifer D'SouzaDepartment of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA.
Miatta BuxtonDepartment of Epidemiology, University of Michigan, Ann Arbor, Michigan, USA.
Abhijit V KshirsagarDivision of Nephrology and Hypertension, Department of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA.
Lawrence S EngelDepartments of Epidemiology and Environmental Sciences and Engineering, University of North Carolina, Chapel Hill, North Carolina, USA.
Cassandra R O'LenickDepartments of Epidemiology and Environmental Sciences and Engineering, University of North Carolina, Chapel Hill, North Carolina, USA.
William E SmoyerDepartment of Pediatrics, Ohio State University, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
Jon KleinDivision of Nephrology and Hypertension, Department of Medicine, Christina Lee Brown Environment Institute, University of Louisville School of Medicine, Louisville, Kentucky, USA.
Wenjun JuDepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Sean EddyDepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Margaret HelmuthDepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Laura H MarianiDepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Matthias KretzlerDepartment of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.
Howard TrachtmanDivision of Nephrology, Department of Pediatrics, University of Michigan, Ann Arbor, Michigan, USA.

Funding

UNC-CH CENTER FOR ENVIRONMENTAL HEALTH &SUSCEPTIBILITYP30ES010126 · NIEHS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Stephanie Engel · 2001 to 2026
$36.3M
Training Program in Clinical & Translationa Research in Human Glomerular DiseaseU54DK083912 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GIPSON, DEBBIE S · 2009 to 2023
$20.3M
CureGNU24DK100845 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CRYSTAL A. GADEGBEKU, Laura H Mariani · 2019 to 2026
$12.1M
The Columbia PCC for CureGN: the Cure Glomerulonephropathy networkU01DK100876 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Andrew Stephen Bomback, ALI G GHARAVI · 2019 to 2026
$8.5M
CureGN-Penn PCCU01DK100846 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI LAWRENCE B. HOLZMAN · 2019 to 2026
$8.3M
CUREGN 3.0 - Pediatric Nephrology Consortium - PCCU01DK100866 · NIDDK · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI Laurence A Greenbaum, Jon Klein · 2019 to 2026
$7.7M
CureGN-3: UNCPCCU01DK100867 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Vimal Kumar Derebail, Ronald J Falk · 2019 to 2026
$6.7M
GDPrimeUM1DK100845 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GIPSON, DEBBIE S, KRETZLER, MATTHIAS · 2013 to 2018
$6.4M
Primary Outcomes in Glomerulonephritis Study (PROGRESS)UM1DK100846 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI HOLZMAN, LAWRENCE B. · 2013 to 2018
$5.8M
Integrative Proteomics & Metabolomics for Pediatric Glomerula Disease BiomarkersUM1DK100866 · NIDDK · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI GREENBAUM, LAURENCE A, SMOYER, WILLIAM E · 2013 to 2018
$5.5M
Advancing Clinical Research in Primary Glomerular Diseases (UM1)UM1DK100876 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GHARAVI, ALI G · 2013 to 2018
$4.8M
GDCN Clinical Center-Advancing Clinical Research in Primary Glomerular DiseasesUM1DK100867 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FALK, RONALD J · 2013 to 2018
$4.0M
NIDDK NIH HHS U01 DK100846NIDDK NIH HHS U01 DK100866NIDDK NIH HHS U01 DK100867NIDDK NIH HHS U01 DK100876NIDDK NIH HHS U01 DK130044NIDDK NIH HHS U24 DK100845NIDDK NIH HHS U54 DK083912NIDDK NIH HHS UM1 DK100845NIDDK NIH HHS UM1 DK100846NIDDK NIH HHS UM1 DK100866NIDDK NIH HHS UM1 DK100867NIDDK NIH HHS UM1 DK100876NIEHS NIH HHS P30 ES010126
6 · The paper itself

Abstract

Introduction: Environmental contributors to kidney disease progression remain elusive. We explored how residential air pollution affects disease progression in patients with primary glomerulopathies. Methods: Nephrotic Syndrome Study Network (NEPTUNE) and CureGlomerulonephropathy (CureGN) participants with residential census tract data and ≥2 years of follow-up were included. Using Cox proportional hazards models, the associations per doubling in annual average baseline concentrations of total particulate matter with diameter ≤2.5 μm (PM Results: PM Conclusion: Elevated exposure to select air pollutants is associated with increased risk of disease progression and systemic inflammation in patients with primary.

Indexed as

black carbonexposureskidneysPM2.5progressionsulfates

Identifiers

PMID39156153
PMCPMC11328569

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.