Trial reportAmerican journal of physiology. Regulatory, integrative and comparative physiology2024
Low-dose sufentanil does not affect tolerance to LBNP-induced central hypovolemia or blood pressure responses during a cold pressor test.
Caitlin P Jarrard, Zachary J McKenna, Whitley C Atkins, Josh Foster, Joseph M Hendrix, Noah P Jouett, Zachary R Oldham, Benjamin J LeBlanc, Joseph C Watso, Craig G Crandall
Abstract readRandomized Controlled Trial
In one paragraphTrial report in American journal of physiology. Regulatory, integrative and comparative physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
10 authors.
Caitlin P JarrardInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.ORCID 0000-0002-6457-6805 Zachary J McKennaInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.ORCID 0000-0003-2502-8870 Whitley C AtkinsInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.ORCID 0000-0003-1610-048X Josh FosterInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.
Joseph M HendrixInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.ORCID 0000-0003-0216-954X Noah P JouettDepartment of Neurology, University of Texas Southwestern Medical Center, Dallas, Texas, United States.ORCID 0000-0001-6147-6537 Zachary R OldhamInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.
Benjamin J LeBlancUniversity of Texas Southwestern Medical School, University of Texas Southwestern Medical Center, Dallas, Texas, United States.
Joseph C WatsoInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.ORCID 0000-0001-7840-0643 Craig G CrandallInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.ORCID 0000-0001-7792-9713 Funding
Time-Efficient Inspiratory Muscle Strength Training as a New Approach to Lower Blood Pressure, Improve Respiratory Function, and Reduce Exertional Dyspnea in Adults with ObesityK01HL160772 · NHLBI · FLORIDA STATE UNIVERSITY · PI Joseph Watso · 2022 to 2026
$693kKetamine-induced Hypertensive Episodes: Adverse Central and Peripheral Neurovascular ActionsF32HL154559 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI WATSO, JOSEPH · 2021 to 2021
$50kAmerican Heart Association (AHA) 23CDA1037938Foundation for the National Institutes of Health (FNIH) K01HL160772NHLBI NIH HHS F32 HL154559NHLBI NIH HHS K01 HL160772NIEHS NIH HHS 27306C0004United States Special Operations Command W81XWH-22-C-0004
6 · The paper itselfAbstract
Hemorrhage is a leading cause of death in the prehospital setting. Since trauma-induced pain often accompanies a hemorrhagic insult, the administered pain medication must not interfere with critical autonomic regulation of arterial blood pressure and vital organ perfusion. The purpose of this study was to test two unrelated hypotheses:
Indexed as
Analgesics, OpioidBlood PressureCross-Over StudiesHypovolemiaLower Body Negative PressureSufentanilAdministration, SublingualAdultCold TemperatureDouble-Blind MethodFemaleHeart RateHumansMalePain PerceptionPain ThresholdAnalgesics, OpioidSufentanilcardiovascularcold pressor testhemorrhageLBNPsufentanil
Identifiers
PMID39155710
PMCPMC11563645
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