Evidence map›Paper›PMID 39155569›Full record

ArticleThe Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology2024

Diagnostic Efficacy of Cell Block and Liquid-Based Cytology for Endoscopic Ultrasound-Guided Fine Needle Aspiration in Pancreatic Tumors.

Ali Şenkaya, Ferit Çelik, Deniz Nart, Nevin Oruç, Aydın Ahmet, Fatih Tekin, İlker Turan

Abstract readEvaluation Study
In one paragraph

Article in The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ali ŞenkayaDepartment of Gastroenterology, University of Health Sciences İzmir Bozyaka Training and Education Hospital, İzmir, Türkiye.
Ferit ÇelikDepartment of Gastroenterology, Bakırçay University Çiğli Training and Education Hospital, İzmir, Türkiye.
Deniz NartDepartment of Pathology, Ege University, Faculty of Medicine, İzmir, Türkiye.
Nevin OruçDivision of Gastroenterology, Department of Internal Medicine, Ege University, Faculty of Medicine, İzmir, Türkiye.
Aydın AhmetDivision of Gastroenterology, Department of Internal Medicine, Ege University, Faculty of Medicine, İzmir, Türkiye.
Fatih TekinDivision of Gastroenterology, Department of Internal Medicine, Ege University, Faculty of Medicine, İzmir, Türkiye.
İlker TuranDivision of Gastroenterology, Department of Internal Medicine, Ege University, Faculty of Medicine, İzmir, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to evaluate the diagnostic efficacy of cell block (CB) and liquid-based cytology (LBC) for endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) in pancreatic tumors. The study included patients who underwent EUS-FNA for pancreatic tumors between January 2015 and February 2021 and whose cytology samples were both processed for LBC and CB. Data of 390 patients (220 men, mean age: 64.2 ± 11.4 years) were retrospectively analyzed. Of the detected lesions (size: 17-120 mm; mean: 39.9 ± 13.9 mm), 220 (56.4%) were located in the head and uncinate process of the pancreas. Lesions in 339 (86.9%) patients were diagnosed as malignant using CB and/or LBC and suspicious for malignancy in 44 (11.3%) patients. In 7 patients with non-diagnostic (6 cases) or negative for malignancy (1 case) EUS-FNA results using both methods, the diagnosis of malignancy was established via ultrasound-guided percutaneous biopsy. Malignancy was detected in 324 (92.4%), 313 (87.9%), and 298 (87.9%) patients using CB, LBC, and both CB and LBC, respectively. Final diagnosis was obtained in 339 (98%) patients by using CB and/or LBC. The combined use of the both methods exhibited significantly superior diagnostic accuracy compared with CB and LBC alone (P < .001). Liquid-based cytology and CB exhibit high diagnostic accuracy for the detection of pancreatic tumors in patients undergoing EUS-FNA. The combined use of both methods showed a significantly higher diagnostic accuracy than LBC and CB alone.

Indexed as

Endoscopic Ultrasound-Guided Fine Needle AspirationPancreatic NeoplasmsAgedFemaleHumansLiquid BiopsyMaleMiddle AgedPancreasRetrospective StudiesSensitivity and Specificity

Identifiers

PMID39155569
PMCPMC11363155

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.