Evidence map›Paper›PMID 39155343›Full record

ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2024

Bacteroides fragilis in saliva: investigating links with ulcerative colitis.

Samin Zamani, Sima Besharat, Nasser Behnampour, Armina Behnam, Negar Asgari, Nazanin Mortazavi

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Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Samin ZamaniDepartment of Microbiology, School of Medicine, Golestan University of Medical Sciences, Gorgan, Iran.ORCID http://orcid.org/0000-0001-7503-7228
Sima BesharatGolestan Research Center of Gastroentrology and Hepatology, Golestan University of Medical Sciences, Gorgan, Iran.ORCID http://orcid.org/0000-0002-0540-6056
Nasser BehnampourHealth Management and Social Development Research Center, Golestan University of Medical Sciences, Gorgan, Iran.ORCID http://orcid.org/0000-0003-1668-8922
Armina BehnamDental Research Center, Golestan University of Medical Sciences, Gorgan, Iran.
Negar AsgariInfectious Diseases Research Center, Golestan University of Medical Sciences, Gorgan, Iran.ORCID http://orcid.org/0000-0002-0595-1089
Nazanin MortazaviDental Research Center, Golestan University of Medical Sciences, Gorgan, Iran. mortazavi_nazanin@yahoo.com.ORCID http://orcid.org/0000-0001-9479-0207

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUlcerative colitis (UC) is a long-term bowel inflammation of unknown cause. Recent research points to gut microbiota, especially Enterotoxigenic Bacteroides fragilis (ETBF), in UC's development. This study examined the presence of Bacteroides fragilis (B. fragilis) and ETBF in the saliva of UC patients and Healthy Controls (HCs) in Iran.

methodsA total of 40 UC patients and 40 healthy controls were included in the study. Saliva samples were collected and analyzed for the presence of B. fragilis and ETBF using real-time polymerase chain reaction (PCR).

resultsB. fragilis was more prevalent in HCs (70%) than UC patients (67.5%), but not significantly (p = 0.809). ETBF was significantly more prevalent in UC patients (50%) than HCs (10%) (p < 0.0001). The mean count of B. fragilis was higher in UC patients, but not significantly (p = 0.47). However, the mean count of ETBF was significantly higher in UC patients (p = 0.000089). In terms of gender, the number of B. fragilis in women was not significant (p = 0.16), but the number of ETBF was significantly higher in women with UC (p = 0.000458). For men, no significant differences were observed.

conclusionsThe present study suggest a higher prevalence of B. fragilis observed in UC patients compared to HCs. Further research is needed to confirm these findings and explore potential mechanisms underlying this association.

Indexed as

Bacteroides fragilisBacteroides InfectionsColitis, UlcerativeSalivaAdultCase-Control StudiesFemaleHumansIranMaleMiddle AgedYoung AdultBacteroides fragilisBacteroides fragilis toxinColitisUlcerative

Identifiers

PMID39155343
PMCPMC11711552

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