Evidence map›Paper›PMID 39154887›Full record

ArticleAmerican journal of kidney diseases : the official journal of the National Kidney Foundation2025

Effect of Dual RAAS Blockade and Intensive BP Lowering on Risk of End-Stage Kidney Disease and Death in Autosomal Dominant Polycystic Kidney Disease: Long-term Follow-up of the HALT-PKD Trials.

Elaine Ku, Timothy P Copeland, Charles E McCulloch, Kaleab Z Abebe, Michel Chonchol, Ronald D Perrone, Frederic F Rahbari-Oskoui, Alan S L Yu, Theodore Steinman, Arlene Chapman and 1 more

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of kidney diseases : the official journal of the National Kidney Foundation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Renal blood flow and progression to kidney failure in ADPKD.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2026
    Observational
  3. Cardiovascular Complications in ADPKD.Kidney international reports · 2025
    Review
  4. Impact of intensive blood pressure control on kidney outcomes.Current opinion in nephrology and hypertension · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Elaine KuDivision of Nephrology, Department of Medicine, University of California, San Francisco, San Francisco, California; Department of Pediatrics, Division of Pediatric Nephrology, University of California, San Francisco, San Francisco, California; Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California. Electronic address: elaine.ku@ucsf.edu.
Timothy P CopelandDivision of Nephrology, Department of Medicine, University of California, San Francisco, San Francisco, California.
Charles E McCullochDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California.
Kaleab Z AbebeCenter for Biostatistics & Qualitative Methodology, Division of General Internal Medicine, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Michel ChoncholDivision of Renal Diseases and Hypertension, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
Ronald D PerroneDivision of Nephrology, Department of Medicine, Tufts Medical Center, Boston, Massachusetts.
Frederic F Rahbari-OskouiDivision of Nephrology, Department of Medicine, Emory University, Atlanta, Georgia.
Alan S L YuDivision of Nephrology, Department of Medicine, University of Kansas Medical Center, Kansas City, Kansas.
Theodore SteinmanSchool of Medicine, Harvard University, Boston, Massachusetts.
Arlene ChapmanDepartment of Medicine, Division of Nephrology, University of Chicago, Chicago, Illinois.
Mark J SarnakDivision of Nephrology, Department of Medicine, Tufts Medical Center, Boston, Massachusetts.

Funding

Harvard Clinical and Translational Science CenterUL1TR001102 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2013 to 2017
$106.2M
HARVARD CLINICAL AND TRANSLATIONAL SCIENCE CENTER (UL1)UL1RR025758 · NCRR · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2008 to 2011
$91.4M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR025780 · NCRR · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2008 to 2011
$61.3M
ZOPOLRESTAT PHARMACOKINETICS IN DIABETICS WITH VARYING RENAL FUNCTIONM01RR000051 · NCRR · UNIVERSITY OF COLORADO DENVER · PI KOSMISKI, LISA A. · 1985 to 2008
$52.6M
Colorado Clinical and Translational Sciences InstituteUL1TR001082 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2013 to 2017
$48.0M
ZINC STATUS AND T CELL DISORDER IN MILD HUMAN ZINC DEFICIENCYM01RR001032 · NCRR · BETH ISRAEL DEACONESS MEDICAL CENTER · PI MANTZOROS, CHRISTOS S · 1985 to 2008
$32.3M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR025008 · NCRR · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2007 to 2011
$29.0M
Tufts Clinical and Translational Research InstituteUL1TR001064 · NCATS · TUFTS UNIVERSITY BOSTON · PI SELKER, HARRY P. · 2013 to 2017
$26.4M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
X LINKED NYSTAGMUS SYNDROME WITH FEATURES OF ALBINISMM01RR000039 · NCRR · EMORY UNIVERSITY · PI VACCARINO, VIOLA · 1985 to 2007
$21.3M
TUFTS CLINICAL AND TRANSLATION SCIENCE INSTITUTE (UL1): BPCAUL1RR025752 · NCRR · TUFTS UNIVERSITY BOSTON · PI SELKER, HARRY P. · 2008 to 2011
$17.6M
Heartland Institute for Clinical and Translational ResearchUL1TR000001 · NCATS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI BAROHN, RICHARD J. · 2012 to 2015
$13.0M
NCATS NIH HHS UL1 TR000001NCATS NIH HHS UL1 TR000454NCATS NIH HHS UL1 TR001064NCATS NIH HHS UL1 TR001082NCATS NIH HHS UL1 TR001102NCRR NIH HHS M01 RR000039NCRR NIH HHS M01 RR000051NCRR NIH HHS M01 RR000054NCRR NIH HHS M01 RR001032NCRR NIH HHS M01 RR023940NCRR NIH HHS UL1 RR025008NCRR NIH HHS UL1 RR025752NCRR NIH HHS UL1 RR025758NCRR NIH HHS UL1 RR025780NCRR NIH HHS UL1 RR033179NIDDK NIH HHS R01 DK121904NIDDK NIH HHS U01 DK062402NIDDK NIH HHS U01 DK062408NIDDK NIH HHS U01 DK062410NIDDK NIH HHS U01 DK062411NIDDK NIH HHS U01 DK082230
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39154887
PMCPMC12097138

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.