Evidence map›Paper›PMID 39154739›Full record

ArticleThe Journal of pediatrics2024

Recall of Flavor at First E-cigarette Use and Its Association with E-cigarette Progression: The Mediating Effects of First Sensory Experience.

Jessica L Barrington-Trimis, Mike Stoolmiller, Erin A Vogel, Alyssa Harlow, Alayna P Tackett, Jennifer B Unger, Rob McConnell, Adam M Leventhal, Janet Audrain-McGovern, James D Sargent

Abstract read
In one paragraph

Article in The Journal of pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jessica L Barrington-TrimisDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA; Institute for Addiction Science, University of Southern California, Los Angeles, CA. Electronic address: jtrimis@usc.edu.
Mike StoolmillerBoston University, Wheelock College of Education and Human Development, Boston, MA.
Erin A VogelTSET Health Promotion Research Center, Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK.
Alyssa HarlowDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA; Institute for Addiction Science, University of Southern California, Los Angeles, CA.
Alayna P TackettThe Center for Tobacco Research, The James Comprehensive Cancer Center, The Ohio State University Wexner Medical Center, Columbus, OH.
Jennifer B UngerDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA; Institute for Addiction Science, University of Southern California, Los Angeles, CA.
Rob McConnellDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA.
Adam M LeventhalDepartment of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA; Institute for Addiction Science, University of Southern California, Los Angeles, CA.
Janet Audrain-McGovernDepartment of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
James D SargentDepartment of Biomedical Data Sciences, C. Everett Koop Institute at Dartmouth, Geisel School of Medicine, Hanover, NH.

Funding

USC Tobacco Center of Regulatory ScienceU54CA180905 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI John R Monterosso · 2018 to 2026
$39.0M
Vaping Nicotine and Cannabis Across Adolescence and Young AdulthoodR01CA229617 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BARRINGTON-TRIMIS, JESSICA LOUISE, LEVENTHAL, ADAM MATTHEW · 2019 to 2024
$4.3M
Tobacco Use Treatment Research for Vulnerable PopulationsK24DA048160 · NIDA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Adam Matthew Leventhal · 2019 to 2026
$1.4M
Understanding Transitions from Vaping to Smoking Across AdolescenceK01DA042950 · NIDA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BARRINGTON-TRIMIS, JESSICA LOUISE · 2017 to 2021
$1.0M
Identifying and Addressing the Effects of Social Media Use on Young Adults' E-Cigarette Use: A Solutions-Oriented ApproachK01DA055073 · NIDA · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI Erin Alyssa Vogel · 2023 to 2026
$764k
NCI NIH HHS R01 CA229617NCI NIH HHS U54 CA180905NIDA NIH HHS K01 DA042950NIDA NIH HHS K01 DA055073NIDA NIH HHS K24 DA048160
6 · The paper itself

Abstract

objectiveTo test whether the association between flavor at first vape and continued use is mediated through subjective experience at first vape. STUDY

designIn a 2020 cross-sectional survey, 955 young adult ever-vapers recalled their first flavor vaped, subjective experiences at first use, current vaping behavior, nicotine dependence, and quit attempts. A latent class model grouped first-use subjective experiences into classes. Two-part negative binomial hurdle models for each vaping behavior evaluated whether the association of first flavor used with vaping outcomes was mediated by positive experience.

resultsFour latent classes (positive, positive and negative, negative, and minimal experience) were further reduced to "any positive experience" (only positive, positive and negative) vs "no positive experience" (negative or minimal). Class membership mediated the association of first flavor used (mint/menthol/ice [ie, "cooling"] or sweet vs other) with each vaping outcome. For example, cooling flavor (vs. other) was associated with positive class membership (OR = 3.5; 95% CI: 1.5, 8.1), which was then associated with any past 30-day vaping (OR = 3.9; 95% CI: 2.7, 5.8) and greater number of vaping days among current vapers (RR = 1.9; 95% CI: 1.3, 2.7) in the two-part hurdle model. Similar results were observed for nicotine dependence and quit attempts, and for sweet (vs other) flavor for any dependence or quit attempts, but not number of dependence symptoms or quit attempts.

conclusionsUse of a cooling or sweet flavor at first use was associated with having a positive first vaping sensory experience, and then greater likelihood as a young adult of reporting past 30-day vaping, more vaping days, and greater risk for nicotine dependence, suggesting a key mediating role of first use experience.

Indexed as

Electronic Nicotine Delivery SystemsFlavoring AgentsVapingAdolescentAdultCross-Sectional StudiesFemaleHumansMaleTobacco Use DisorderYoung AdultFlavoring Agents

Identifiers

PMID39154739
PMCPMC11837250

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.