Evidence map›Paper›PMID 39154318›Full record

ArticleLa Radiologia medica2024

MRI-guided transrectal prostate laser ablation for benign prostatic hypertrophy: a retrospective cohort study.

Aaron Harman, Robert Toth, Zahra Mobley, Donnie Sartin, Ara Karamanian

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Article in La Radiologia medica, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aaron HarmanHalo Prostate Laser Center, 6624 Fannin St., Suite 2580, Houston, TX, 77030, USA. aaron.harman@halodx.com.ORCID http://orcid.org/0000-0003-1564-4338
Robert TothThetaTech AI, Piscataway, NJ, USA.
Zahra MobleyHalo Prostate Laser Center, 6624 Fannin St., Suite 2580, Houston, TX, 77030, USA.
Donnie SartinHalo Prostate Laser Center, 6624 Fannin St., Suite 2580, Houston, TX, 77030, USA.
Ara KaramanianHalo Prostate Laser Center, 6624 Fannin St., Suite 2580, Houston, TX, 77030, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate whether MRI-guided transrectal laser ablation is safe and effective for the treatment of lower urinary tract symptoms caused by BPH. MATERIALS AND

methodsThis single-center retrospective cohort study evaluated men who underwent MRI-guided transrectal laser ablation for BPH between February 2017 and July 2021. Age, prostate-specific antigen, prostate volume, prior surgical BPH treatments if any, International Prostate Symptom Score (IPSS) and Sexual Health Inventory of Men (SHIM) were collected. The primary outcome measures assessed were change in IPSS and SHIM 6, 12 and 24 months after laser ablation and adverse events.

resultsFifty-two patients were included, having completed at least one follow-up survey. The mean patient age was 62.9 ± 5.7 years, and mean prostate volume was 80.2 ± 39.2 cc. Eighteen patients (34.6%) had received a prior BPH treatment. The IPSS scores dropped an average of 16.7 ± 7.0 (p < 0.001), 16.9 ± 7.5 (p < 0.001) and 17.1 ± 7.2 (p < 0.001) points from baseline at 6, 12 and 24 months, respectively. There was no statistically significant difference in IPSS score drop between patients who had received a prior BPH procedure and those who had not (p = 0.628). The SHIM scores showed a statistically insignificant increase at all time points. Nineteen patients (36.5%) reported a complication. There were 12 grade II complications (23%) and seven grade I complications (13.5%). There were no grade III or higher complications.

conclusionTransrectal MRI-guided focal laser ablation is safe and effective for the treatment of lower urinary tract symptoms caused by BPH, with a significant improvement in symptom severity after 2 years.

Indexed as

Laser TherapyProstatic HyperplasiaAgedHumansLower Urinary Tract SymptomsMagnetic Resonance ImagingMagnetic Resonance Imaging, InterventionalMaleMiddle AgedRetrospective StudiesTreatment OutcomeBenign prostatic hypertrophyLower urinary tract symptomsMinimally invasive surgeryMRI-guided laser ablation

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.