Evidence map›Paper›PMID 39154012›Full record

SynthesisBMC surgery2024

Primary schwannoma of the thyroid gland: analysis of case characteristics and review of the literature.

Hangjun Ren, Xingguo Cui, Lianmei Zhang

Abstract readSystematic Review
In one paragraph

Synthesis in BMC surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hangjun RenDepartment of General Surgery, The First People's Hospital of Yuhang District, Hangzhou, Zhejiang, 311100, China.
Xingguo CuiDepartment of Thyroid Breast Surgery, Yanbian University Hospital, Yanbian, Jilin, 133000, China.
Lianmei ZhangDepartment of Thyroid Breast Surgery, Yanbian University Hospital, Yanbian, Jilin, 133000, China. 2224272992@qq.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo improve the characteristics of primary thyroid schwannomas (PTS) and to provide reference basis for clinical diagnosis and treatment.

methodsPubMed was searched for case reports of PTS up to December 2022 using the search terms "Thyroid nerve sheath tumor" or "Thyroid schwannoma" or "Thyroid Neurilemmoma", respectively. 34 cases were screened.

resultsPTS can occur at any age, nodules averaged 3.9 cm. The most common symptoms were voice change and dysphagia. Fine needle aspiration cytology showing spindle-shaped cells should be considered for schwannoma. Most cases underwent thyroid lobectomy or nodule removal with a good prognosis. Tissue types with both Antoni A and Antoni B features are common. Positive immunohistochemical staining for S-100 protein, CD34 and waveform proteins helped confirm the diagnosis.

conclusionsPositive immunohistochemistry for S-100 and wave proteins helps confirm the diagnosis. Preoperative diagnosis is challenging, but pathology and immunohistochemical staining are the gold standard for diagnosis. The first choice of treatment is surgical resection of the nodules, the prognosis is good.

Indexed as

NeurilemmomaThyroid NeoplasmsAdultAgedBiopsy, Fine-NeedleFemaleHumansImmunohistochemistryMaleMiddle AgedPrognosisS100 ProteinsThyroidectomyThyroid GlandS100 ProteinsNeck schwannomaS-100 proteinThyroid nerve sheath tumorThyroid noduleThyroid schwannoma

Identifiers

PMID39154012
PMCPMC11330010

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.