Evidence map›Paper›PMID 39153987›Full record

ArticleSpinal cord series and cases2024

Spinal cord injury in high-risk complex adult spinal deformity surgery: review of incidence and outcomes from the Scoli-RISK-1 study.

Fan Jiang, Hetshree Joshi, Jetan H Badhiwala, Jamie R F Wilson, Lawrence G Lenke, Christopher I Shaffrey, Kenneth M C Cheung, Leah Y Carreon, Mark B Dekutoski, Frank J Schwab and 11 more

Abstract readMulticenter StudyCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Spinal cord series and cases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Fan JiangDepartment of Surgery and Spine Program, University of Toronto, Toronto, ON, Canada.
Hetshree JoshiDepartment of Surgery and Spine Program, University of Toronto, Toronto, ON, Canada.
Jetan H BadhiwalaDepartment of Surgery and Spine Program, University of Toronto, Toronto, ON, Canada.
Jamie R F WilsonDepartment of Surgery and Spine Program, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-3488-7506
Lawrence G LenkeDepartment of Orthopedic Surgery, The Spine Hospital, Columbia University Medical Center, New York, NY, USA.
Christopher I ShaffreyDepartment of Orthopaedic Surgery, Duke University, Durham, NC, USA.
Kenneth M C CheungDepartment of Orthopaedics and Traumatology, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.
Leah Y CarreonNorton Leatherman Spine Center, Louisville, KY, USA.
Mark B DekutoskiThe CORE Institute, Sun City West, AZ, USA.
Frank J SchwabSpine Service, Hospital for Special Surgery, New York, NY, USA.
Oheneba Boachie-AdjeiThe FOCOS Hospital, Pantang West, Republic of Ghana.
Khaled M KebaishDepartment of Orthopaedic Surgery, Johns Hopkins Hospital, Baltimore, MD, USA.
Christopher P AmesDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA, USA.
Sigurd H BervenDepartment of Orthopaedic Surgery, University of California, San Francisco, San Francisco, CA, USA.
Yong QiuSpine Surgery, Drum Tower Hospital of Nanjing University Medical School, Nanjing, Jiangsu, China.
Yukihiro MatsuyamaDepartment of Orthopedic Surgery, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan.
Benny T DahlDivision of Orthopedic Surgery, Texas Children's Hospital, Baylor College of Medicine, Houston & Rigshospitalet, National University of Denmark, Copenhagen, Denmark.
Hossein MehdianThe Centre for Spinal Studies and Surgery, Queen's Medical Centre, Nottingham University Hospitals, Nottingham, UK.
Ferran PelliséHospital Universitari de la Vall d'Hebron, Barcelona, Spain.
Stephen J LewisDepartment of Surgery and Spine Program, University of Toronto, Toronto, ON, Canada.
Michael G FehlingsDepartment of Surgery and Spine Program, University of Toronto, Toronto, ON, Canada. michael.fehlings@uhn.ca.ORCID 0000-0002-5722-6364

Funding

Skeletal Biology and Biomechanics (SBB) CoreP30AR075055 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI EDWARD C HSIAO · 2019 to 2026
$7.1M
AOSpine (AO Spine International) N/ANIAMS NIH HHS P30 AR075055Scoliosis Research Society (SRS) N/A
6 · The paper itself

Abstract

STUDY

designClinical case series.

objectiveTo describe the cause, treatment and outcome of 6 cases of perioperative spinal cord injury (SCI) in high-risk adult deformity surgery.

settingAdult spinal deformity patients were enrolled in the multi-center Scoli-RISK-1 cohort study.

methodsA total of 272 patients who underwent complex adult deformity surgery were enrolled in the prospective, multi-center Scoli-RISK-1 cohort study. Clinical follow up data were available up to a maximum of 2 years after index surgery. Cases of perioperative SCI were identified and an extensive case review was performed.

resultsSix individuals with SCI were identified from the Scoli-RISK-1 database (2.2%). Two cases occurred intraoperatively and four cases occurred postoperatively. The first case was an incomplete SCI due to a direct intraoperative insult and was treated postoperatively with Riluzole. The second SCI case was caused by a compression injury due to overcorrection of the deformity. Three cases of incomplete SCI occurred; one case of postoperative hematoma, one case of proximal junctional kyphosis (PJK) and one case of adjacent segment disc herniation. All cases of post-operative incomplete SCI were managed with revision decompression and resulted in excellent clinical recovery. One case of incomplete SCI resulted from infection and PJK. The patient's treatment was complicated by a delay in revision and the patient suffered persistent neurological deficits up to six weeks following the onset of SCI.

conclusionDespite the low incidence in high-risk adult deformity surgeries, perioperative SCI can result in devastating consequences. Thus, appropriate postoperative care, follow up and timely management of SCI are essential.

Indexed as

Spinal Cord InjuriesAdultAgedCohort StudiesFemaleHumansIncidenceMaleMiddle AgedPostoperative ComplicationsProspective StudiesTreatment Outcome

Identifiers

PMID39153987
PMCPMC11330517

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.