Evidence map›Paper›PMID 39153979›Full record

Observational studyRespiratory research2024

Epidemiology, ventilation management and outcomes of COVID-19 ARDS patients versus patients with ARDS due to pneumonia in the Pre-COVID era.

Fleur-Stefanie L I M van der Ven, Siebe G Blok, Luciano C Azevedo, Giacomo Bellani, Michela Botta, Elisa Estenssoro, Eddy Fan, Juliana Carvalho Ferreira, John G Laffey, Ignacio Martin-Loeches and 17 more

Erratum issued Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in Respiratory research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT05650957 (PRactice of VENTilation in Patients With ARDS Due to COVID-19 Versus ARDS Due to Other Pulmonary Infections), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05650957 completednot on this map

PRactice of VENTilation in Patients With ARDS Due to COVID-19 Versus ARDS Due to Other Pulmonary Infections (PRoVENT-COP)

TypeobservationalSponsorAcademisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)Ran2022 to 2024Enrolled7,145ConditionsAcute Respiratory Distress Syndrome, COVID-19, Pneumonia, Mechanical Ventilation Complication
3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. ARDS and corticosteroids: beyond COVID-19.Pneumonia (Nathan Qld.) · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

27 authors.

Fleur-Stefanie L I M van der Ven *Department of Intensive Care, Amsterdam University Medical Centers, Location 'AMC', Meibergdreef 9, 1105, AZ, Amsterdam, The Netherlands. f.ven@amsterdamumc.nl.
Siebe G Blok *Department of Intensive Care, Amsterdam University Medical Centers, Location 'AMC', Meibergdreef 9, 1105, AZ, Amsterdam, The Netherlands.
Luciano C AzevedoDepartment of Emergency Medicine, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
Giacomo BellaniCentre for Medical Sciences (CISMed), University of Trento, Trento, Italy.
Michela BottaDepartment of Intensive Care, Amsterdam University Medical Centers, Location 'AMC', Meibergdreef 9, 1105, AZ, Amsterdam, The Netherlands.
Elisa EstenssoroDepartment of Intensive Care, Hospital Interzonal de Agudos General San Martin La Plata, Buenos Aires, Argentina.
Eddy FanInterdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada.
Juliana Carvalho FerreiraDepartment of Pulmonology, Instituto Do Coracao (InCor), Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, Brazil.
John G LaffeyDepartment of Anaesthesiology and Intensive Care, Galway University Hospital, Saolta Hospital Group, Galway, Ireland.
Ignacio Martin-LoechesDepartment of Intensive Care, Multidisciplinary Intensive Care Research Organization (MICRO), St James' Hospital, Dublin, Ireland.
Ana MotosDepartement of Pulmonology, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Hospital Clínic de Barcelona, Barcelona, Spain.
Tai PhamEquipe d'Epidémiologie Respiratoire Integrative, Université Paris-Saclay, Paris, France.
Oscar PeñuelasCentro de Investigación Biomédica en Red en Enfermedades Respiratorias (CIBERES), Institute of Health Carlos III, Madrid, Spain.
Antonio PesentiFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Luigi PisaniDepartment of Intensive Care, Amsterdam University Medical Centers, Location 'AMC', Meibergdreef 9, 1105, AZ, Amsterdam, The Netherlands.
Ary Serpa NetoDepartment of Intensive Care, Hospital Israelita Albert Einstein, São Paulo, Brazil.
Marcus J SchultzDepartment of Intensive Care, Amsterdam University Medical Centers, Location 'AMC', Meibergdreef 9, 1105, AZ, Amsterdam, The Netherlands.
Antoni TorresDepartement of Pulmonology, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Hospital Clínic de Barcelona, Barcelona, Spain.
Anissa M TsonasDepartment of Intensive Care, Amsterdam University Medical Centers, Location 'AMC', Meibergdreef 9, 1105, AZ, Amsterdam, The Netherlands.
Frederique PaulusDepartment of Intensive Care, Amsterdam University Medical Centers, Location 'AMC', Meibergdreef 9, 1105, AZ, Amsterdam, The Netherlands.
David M P van MeenenDepartment of Intensive Care, Amsterdam University Medical Centers, Location 'AMC', Meibergdreef 9, 1105, AZ, Amsterdam, The Netherlands.
and for the ERICC–
LUNG SAFE–
PRoVENT–COVID–
EPICCoV–
CIBERESUCICOVID–
SATI–COVID–19–investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVentilation management may differ between COVID-19 ARDS (COVID-ARDS) patients and patients with pre-COVID ARDS (CLASSIC-ARDS); it is uncertain whether associations of ventilation management with outcomes for CLASSIC-ARDS also exist in COVID-ARDS.

methodsIndividual patient data analysis of COVID-ARDS and CLASSIC-ARDS patients in six observational studies of ventilation, four in the COVID-19 pandemic and two pre-pandemic. Descriptive statistics were used to compare epidemiology and ventilation characteristics. The primary endpoint were key ventilation parameters; other outcomes included mortality and ventilator-free days and alive (VFD-60) at day 60.

resultsThis analysis included 6702 COVID-ARDS patients and 1415 CLASSIC-ARDS patients. COVID-ARDS patients received lower median V

conclusionsOur findings show important differences in key ventilation parameters and associations thereof with outcomes between COVID-ARDS and CLASSIC-ARDS.

trial registrationClinicaltrials.gov (identifier NCT05650957), December 14, 2022.

Indexed as

COVID-19PneumoniaRespiration, ArtificialRespiratory Distress SyndromeAdultAgedFemaleHumansMaleMiddle AgedTreatment OutcomeAcute respiratory distress syndromeARDSCOVID–19Critical careMechanical ventilationVentilation management

Identifiers

PMID39153979
PMCPMC11330602

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.