Evidence map›Paper›PMID 39153228›Full record

ArticleExperimental physiology2024

Interference with glutamate antiporter system x

Bradley S Heit, Alex Chu, Alyssa McRay, Janet E Richmond, Charles J Heckman, John Larson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Plasma Cystine as a Marker of Acute Stroke Severity.Diagnostics (Basel, Switzerland) · 2025
    Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bradley S HeitDepartment of Neuroscience and Department of Biomedical Engineering, Northwestern University, Chicago, Illinois, USA.ORCID https://orcid.org/0000-0002-4821-5225
Alex ChuDepartment of Psychiatry, University of Illinois at Chicago, Chicago, Illinois, USA.
Alyssa McRayDepartment of Biological Sciences, University of Illinois at Chicago, Chicago, Illinois, USA.
Janet E RichmondDepartment of Biological Sciences, University of Illinois at Chicago, Chicago, Illinois, USA.
Charles J HeckmanDepartment of Neuroscience and Department of Biomedical Engineering, Northwestern University, Chicago, Illinois, USA.
John LarsonDepartment of Psychiatry, University of Illinois at Chicago, Chicago, Illinois, USA.

Funding

PATHOPHYSIOLOGY AND REHABILITATION OF NEURAL DYSFUNCTIONT32HD007418 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Levi John Hargrove · 1992 to 2026
$6.5M
National Science Foundation 1655494NICHD NIH HHS T32 HD007418NIH HHS T32 HD07418
6 · The paper itself

Abstract

Our group previously showed that genetic or pharmacological inhibition of the cystine/glutamate antiporter, system x

Indexed as

Amino Acid Transport System y+HippocampusHypoxiaLong-Term PotentiationMice, KnockoutAnimalsGlutamic AcidMaleMiceMice, Inbred C57BLReceptors, N-Methyl-D-AspartateSynaptic TransmissionAmino Acid Transport System y+Glutamic AcidReceptors, N-Methyl-D-AspartateSlc7a11 protein, mousecystine/glutamate transporterexcitotoxicityhypoxialong‐term potentiationstroke

Identifiers

PMID39153228
PMCPMC11363115

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.