ArticleExperimental physiology2026
Blood flow restriction: The acute effects of body tilting and reduced gravity analogues on limb occlusion pressure.
Article in Experimental physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Blood flow restriction: The acute effects of body tilting and reduced gravity analogues on limb occlusion pressure.Experimental physiology · 2026Article
- Blood flow restriction exercise during microgravity exposure in parabolic flight.Experimental physiology · 2026Article
- Jumping in simulated lunar gravity with blood flow restriction as a potential exercise countermeasure: The acute physiological effects.Experimental physiology · 2026Article
- Hypogravity simulation using the Variable Gravity Suspension System: A technical report.Experimental physiology · 2026Article
- Individual factors associated with arterial and limb occlusion pressure in blood flow restriction: a scoping review of predictors and measurement methods.Frontiers in physiology · 2026Review
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Authors and funding
3 authors.
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Abstract
Blood flow restriction (BFR) has been identified as a potential countermeasure to mitigate physiological deconditioning during spaceflight. Guidelines recommend that tourniquet pressure be prescribed relative to limb occlusion pressure (LOP); however, it is unclear whether body tilting or reduced gravity analogues influence LOP. We examined LOP at the leg and arm during supine bedrest and bodyweight suspension (BWS) at 6° head-down tilt (HDT), horizontal (0°), and 9.5° head-up tilt (HUT) positions. Twenty-seven adults (age, 26 ± 5 years; height, 1.75 ± 0.08 m; body mass, 73 ± 12 kg) completed all tilts during bedrest. A subgroup (n = 15) additionally completed the tilts during BWS. In each position, LOP was measured twice in the leg and arm using the Delfi Personalized Tourniquet System after 5 min of rest and again after a further 5 min. The LOP at the leg increased significantly from 6° HDT to 9.5° HUT in bedrest and BWS by 9-15 mmHg (Cohen's d = 0.7-1.0). Leg LOP was significantly higher during BWS at horizontal and 9.5° HUT postures relative to the same angles during bedrest by 8 mmHg (Cohen's d = 0.6). Arm LOP remained unchanged between body tilts and analogues. Intraclass correlation coefficients for LOP measurements taken after an initial and subsequent 5 min rest period in all conditions ranged between 0.91-0.95 (leg) and 0.83-0.96 (arm). It is advised that LOP be measured before the application of a vascular occlusion in the same body tilt/setting to which it is applied to minimize discrepancies between the actual and prescribed tourniquet pressure.
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