ArticleInternational journal of clinical pharmacy2024
Characteristics and causes of reported clozapine-related medication errors: analysis of the Ministry of Health database in Saudi Arabia.
Article in International journal of clinical pharmacy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Medication Safety Practice in Selected Saudi Hospitals: Alignment with the World Health Organization Global Medication Safety Challenge-An Exploratory Study.Healthcare (Basel, Switzerland) · 2026Article
- Biologics and biosimilars medication errors in Saudi Arabia: a nationwide retrospective observational real-world study.Frontiers in medicine · 2026Article
- Exploring Medication Errors with Antipsychotics in Saudi Arabia: Insights from a Nationwide Analysis.Healthcare (Basel, Switzerland) · 2025Article
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13 authors.
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Abstract
backgroundClozapine has shown great efficacy in treating treatment-resistant schizophrenia, but it is associated with a variety of medication- related safety problems. Despite this, there remains a lack of research on medication errors (MEs) associated with its use.
aimTo characterize the nature and contributory factors of clozapine-related MEs reported from government hospitals and primary care centres in Saudi Arabia (SA).
methodA cross-sectional analysis was carried out on MEs related to clozapine use reported to the General Administration of Pharmaceutical Care at the Ministry of Health (MOH) in Saudi Arabia between 2018 and 2022. The data were analysed descriptively to examine the nature and contributory factors of MEs.
resultsA total of 1,165 MEs were reported. The majority of reported errors involved patients aged > 18 years old, with 72.2% (n = 841) being male. The central region was found to report errors more frequently (32.3%, n = 376). Pharmacists were reported to detect errors most frequently (59.6%, n = 695). MEs most often occurred in the prescribing stage (77.8%, n = 906), with "missing prescription information" (30.1%, n = 351) being the most frequent finding. The most frequent contributing factor was the lack of policy (33.1%, n = 351). The majority of errors did not reach the patients (92.3%, n = 1,075), and those that did reach patients rarely resulted in harm (0.3%, n = 2).
conclusionThis study identified areas for improvement which could expedite the development of remedial interventions to reduce the risk of errors.
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