Evidence map›Paper›PMID 39153118›Full record

ReviewArchives of dermatological research2024

Adipose-derived stem cell conditioned medium for hair regeneration therapy in alopecia: a review of literature.

Lili Legiawati, Lis Surachmiati Suseno, Irma Bernadette S Sitohang, Shannaz Nadia Yusharyahya, Alessa Fahira, Edwin Ti Ramadan, Kanya Paramastri

Abstract readReview
PubMed Publisher
In one paragraph

Review in Archives of dermatological research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lili LegiawatiDepartment of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia Dr. Cipto Mangunkusumo National General Hospital Jakarta, Diponegoro no. 71 Kenari, Senen, Jakarta, 10430, Indonesia. lililegiawati@yahoo.com.ORCID http://orcid.org/0000-0002-5793-2525
Lis Surachmiati SusenoDepartment of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia Dr. Cipto Mangunkusumo National General Hospital Jakarta, Diponegoro no. 71 Kenari, Senen, Jakarta, 10430, Indonesia.
Irma Bernadette S SitohangDepartment of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia Dr. Cipto Mangunkusumo National General Hospital Jakarta, Diponegoro no. 71 Kenari, Senen, Jakarta, 10430, Indonesia.
Shannaz Nadia YusharyahyaDepartment of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia Dr. Cipto Mangunkusumo National General Hospital Jakarta, Diponegoro no. 71 Kenari, Senen, Jakarta, 10430, Indonesia.
Alessa FahiraDepartment of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia Dr. Cipto Mangunkusumo National General Hospital Jakarta, Diponegoro no. 71 Kenari, Senen, Jakarta, 10430, Indonesia.
Edwin Ti RamadanDepartment of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia Dr. Cipto Mangunkusumo National General Hospital Jakarta, Diponegoro no. 71 Kenari, Senen, Jakarta, 10430, Indonesia.
Kanya ParamastriDepartment of Dermatology and Venereology, Faculty of Medicine, Universitas Indonesia Dr. Cipto Mangunkusumo National General Hospital Jakarta, Diponegoro no. 71 Kenari, Senen, Jakarta, 10430, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To date, therapeutic choices for alopecia have shown limited effectiveness and safety, making the discovery of new therapeutic choices challenging. Adipose-derived stem cells conditioned-medium (ADSC-CM) contain various growth factors released by ADSCs that may support hair regrowth. This literature review aims to discover the effect and clinical impact of ADSC-CM in the treatment of alopecia. A comprehensive literature search was performed through four databases (Pubmed, ScienceDirect, Cochrane, and Scopus) in September 2021. A combination of search terms including "adipose-derived stem cells" and "alopecia" was used. Studies published in English that included ADSC-CM interventions on alopecia of all types were selected and summarized. A total of five studies were selected for review, all of which were case series. All studies showed a positive outcome for intervention. Outcomes measured in the studies include hair count or hair density, hair thickness, anagen, and telogen hair count. No adverse effects were reported from all studies. Limitations lie in the differences in intervention method, application, and length of treatment. ADSC-CM hair regeneration therapy is an effective and safe treatment for alopecia that may be combined with other types of therapy to improve outcomes.

Indexed as

AlopeciaHairRegenerationAdipose TissueCulture Media, ConditionedHair FollicleHumansTreatment OutcomeCulture Media, ConditionedAdipose-derived stem cellsAlopeciaConditioned mediumEfficacySafety

Identifiers

PMID39153118

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.