Trial reportBMC ophthalmology2024
Safety and prognosis of phacoemulsification using active sentry and active fluidics with different IOP settings - a randomized, controlled study.
Trial report in BMC ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- The effect of intraocular pressure during phacoemulsification in patients with either diabetic retinopathy or glaucoma; a randomized controlled feasibility trial.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025Trial
- Comparison of Post-Operative Outcomes between IOP-20 and IOP-50 in Phacoemulsification with Active Fluidics System: Randomized Single Blinded Trial.Clinical ophthalmology (Auckland, N.Z.) · 2025Trial
- Posterior vitreous detachment following phacoemulsification under low intraocular pressure: a population-based OCT study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Observational
- Clinical outcomes of the eight-chop technique in white cataract: a retrospective case series.BMC ophthalmology · 2026Observational
- Occlusion Break Surge and Anterior Chamber Stability in the Intraocular Environment of Modern Phacoemulsification: A Narrative Review.Medicina (Kaunas, Lithuania) · 2026Review
- Postoperative Flare and Corneal Endothelial Cell Loss After Eight-Chop Technique Phacoemulsification: A Prospective Observational Study.Journal of clinical medicine · 2026Article
- Does Further Lowering Intraoperative Intraocular Pressure Reduce Surgical Invasiveness in Active-Fluidics Eight-Chop Phacoemulsification? A Fellow-Eye Comparative Study.Journal of clinical medicine · 2026Article
- The Eight‑Chop Technique in Cataract Surgery: A Conceptual and Narrative Review of a Segmentation‑First Strategy.Clinical ophthalmology (Auckland, N.Z.) · 2026Review
- Cataract Surgery in Pseudoexfoliation Syndrome Using the Eight-Chop Technique.Journal of personalized medicine · 2025Article
- Enhancing Phacoemulsification Safety: How Low Fluidic Settings Influence Active Surge Mitigation Actuation.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
- Physiological Intraocular Pressure in Cataract Surgery: A Comparative Consecutive Case Series Study.Clinical ophthalmology (Auckland, N.Z.) · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
purposeTo explore the impact of different intraoperative intraocular pressure (IOP) settings on the safety and prognosis in phacoemulsification.
methodsAge related cataract patients who met the inclusion criteria and underwent phacoemulsification by using active sentry handpiece and active fluidics system. According to different intraoperative IOP settings during surgery, they were randomly divided into two groups: the 20mmHg group and the 60mmHg group. The best corrected visual acuity (BCVA), cumulative dissipated energy (CDE), total U/S time, active surge mitigation (ASM), estimated fluid usage (EFU) as well as the changes in corneal thickness (CT), corneal epithelial layer thickness (CELT) and endothelial cell density (ECD) were collected. The post-operative follow-up was only 1 day.
resultsA total of 110 cases (110 eyes) were included in the study. There were 55 eyes in each group. There was no statistically significant difference in postoperative BCVA (p = 0.839). The CDE, total U/S time and EFU during surgery were (5.22 ± 3.31), (30.60 ± 15.06), (45.07 ± 12.68) and (4.70 ± 2.83), (27.39 ± 13.75), (42.38 ± 11.93) in the 20mmHg group and 60mmHg group (p = 0.381, 0.246, 0.254). The ASM during surgery in the 20mmHg group and 60mmHg group were (0.95 ± 2.77) and (7.24 ± 6.34), respectively. The 20mmHg group showed a significant decrease in ASM (p < 0.001). There was no statistically significant difference in the changes in CT, CELT and ECD before and after surgery between the two groups (p = 0.913, 0.825, 0.624). Both groups did not experience any intraoperative complications, such as posterior capsule rupture.
conclusionA lower IOP setting of 20 mmHg can significantly reduce the occurrence of intraoperative surges during phacoemulsification. And there was no increase in rate of complications.
trial registrationThe trial registration number is ChiCTR2100050240. The registered date is August 24th, 2021.
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