ArticleNature microbiology2024
Virulence of banana wilt-causing fungal pathogen Fusarium oxysporum tropical race 4 is mediated by nitric oxide biosynthesis and accessory genes.
Article in Nature microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 22 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed.
- Pathogenicity and Virulence ofVirulence · 2026Review
- Virulence determinants of Fusarium oxysporum for clinical infections.PLoS pathogens · 2026Article
- Genome-Wide Analysis ofJournal of fungi (Basel, Switzerland) · 2026Article
- Ratiometric Mycotoxin Detection in Living Plants With Dual-Emissive Nanosensors.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Adaptive Responses of Tropical Crops: A Multi-Scale Omics Integrated Perspective.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Deciphering the mechanism of selenium-induced resistance to TR4 in bananas via proteomic profiling.BMC plant biology · 2026Article
- Streptomyces-induced Glycerol-3-Phosphate enriches beneficial microbiota to enhance resistance against banana Fusarium wilt.Microbiome · 2026Article
- Genome reshaping by Helitron transposons in Fusarium oxysporum TR4 affects secondary metabolism but not virulence.Nature communications · 2026Article
- Host suppression of the novel virulent effector FocSP1 improves banana resistance toHorticulture research · 2026Article
- Integration of NO and HPlant communications · 2026Review
- Integrated metabolomics and metagenomics uncover pathogenic mechanisms of Fusarium wilt and faba bean defense responses.NPJ science of food · 2026Article
- Navigating Fusarium wilt of bananas: a ready-to-use subset of resistantFrontiers in plant science · 2026Review
- A binary-distributed effector modulates fungal host preference for drosophilids by targeting a lineage-specific immune factor.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Single-cell transcriptome atlas unveils transcriptional regulation networks of banana root tips in response toHorticulture research · 2025Article
- Transposons and accessory genes drive adaptation in a clonally evolving fungal pathogen.Nature communications · 2025Article
- Methods to Observe Plant Tissue Colonization by Fusarium oxysporum.Current protocols · 2025Article
- Long-Read Draft Genome Sequences of TwoJournal of fungi (Basel, Switzerland) · 2025Article
- Shaping the future of bananas: advancing genetic trait regulation and breeding in the postgenomics era.Horticulture research · 2025Article
- Discovery of MK8383s with Antifungal Activity from Mangrove Endophytic FungiMarine drugs · 2025Article
- Identification of a ubiquitin-protein ligase MaUPL6 modulating the response to Fusarium wilt in banana.Molecular horticulture · 2025Article
Corrections and comments
- Erratum issued
- Update of
Authors and funding
15 authors.
Funding
Abstract
Fusarium wilt of banana, caused by Fusarium oxysporum f. sp. cubense (Foc), is one of the most damaging plant diseases known. Foc race 1 (R1) decimated the Gros Michel-based banana (Musa acuminata) trade, and now Foc tropical race 4 (TR4) threatens global production of its replacement, the Cavendish banana. Here population genomics revealed that all Cavendish banana-infecting Foc race 4 strains share an evolutionary origin distinct from that of R1 strains. Although TR4 lacks accessory chromosomes, it contains accessory genes at the ends of some core chromosomes that are enriched for virulence and mitochondria-related functions. Meta-transcriptomics revealed the unique induction of the entire mitochondrion-localized nitric oxide (NO) biosynthesis pathway upon TR4 infection. Empirically, we confirmed the unique induction of a NO burst in TR4, suggesting that nitrosative pressure may contribute to virulence. Targeted mutagenesis demonstrated the functional importance of fungal NO production and the accessory gene SIX4 as virulence factors.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.