Evidence map›Paper›PMID 39151953›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2024

Zinc-Finger Protein ZFP488 Regulates the Timing of Oligodendrocyte Myelination and Remyelination.

Siying Cui, Tong Chen, Dazhuan Xin, Fangbing Chen, Xiaowen Zhong, Chen Dong, Xiang Chen, Huiyao Chen, Wenhao Zhou, Yifeng Lin and 1 more

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In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Siying CuiKey Laboratory of Birth Defects, Children's Hospital of Fudan University, Shanghai 201102, China.
Tong ChenKey Laboratory of Birth Defects, Children's Hospital of Fudan University, Shanghai 201102, China.
Dazhuan XinDepartment of Pediatrics, Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229.
Fangbing ChenKey Laboratory of Birth Defects, Children's Hospital of Fudan University, Shanghai 201102, China.
Xiaowen ZhongDepartment of Pediatrics, Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229.
Chen DongKey Laboratory of Birth Defects, Children's Hospital of Fudan University, Shanghai 201102, China.
Xiang ChenKey Laboratory of Birth Defects, Children's Hospital of Fudan University, Shanghai 201102, China.
Huiyao ChenKey Laboratory of Birth Defects, Children's Hospital of Fudan University, Shanghai 201102, China.
Wenhao ZhouKey Laboratory of Birth Defects, Children's Hospital of Fudan University, Shanghai 201102, China.
Yifeng LinKey Laboratory of Birth Defects, Children's Hospital of Fudan University, Shanghai 201102, China richard.lu@cchmc.org irenelin2002@163.com.
Q Richard LuDepartment of Pediatrics, Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio 45229 richard.lu@cchmc.org irenelin2002@163.com.ORCID 0000-0001-6846-9014

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oligodendrocyte myelination and remyelination after injury are intricately regulated by various intrinsic and extrinsic factors, including transcriptional regulators. Among these, the zinc-finger protein ZFP488 is an oligodendrocyte-enriched transcriptional regulator that promotes oligodendrocyte differentiation in the developing neural tube and in oligodendroglial cell lines. However, the specific in vivo genetic requirements for ZFP488 during oligodendrocyte development and remyelination have not been defined. To address this gap, we generated a lineage-traceable

Indexed as

Myelin SheathOligodendrogliaRemyelinationAnimalsCell DifferentiationDemyelinating DiseasesFemaleMaleMiceMice, Inbred C57BLMice, KnockoutRepressor ProteinsRepressor ProteinsZfp488 protein, mousecentral nervous systemmyelinationoligodendrocyteremyelinationtranscription factorZn-finger protein ZFP488

Identifiers

PMID39151953
PMCPMC11426379

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.