Evidence map›Paper›PMID 39150783›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Light regulates widespread plant alternative polyadenylation through the chloroplast.

M Guillermina Kubaczka, Micaela A Godoy Herz, Wei-Chun Chen, Dinghai Zheng, Ezequiel Petrillo, Bin Tian, Alberto R Kornblihtt

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

M Guillermina KubaczkaUniversidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Departamento de Fisiología, Biología Molecular y Celular and CONICET-UBA, Instituto de Fisiología, Biología Molecular y Neurociencias, Buenos Aires 1428, Argentina.
Micaela A Godoy HerzUniversidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Departamento de Fisiología, Biología Molecular y Celular and CONICET-UBA, Instituto de Fisiología, Biología Molecular y Neurociencias, Buenos Aires 1428, Argentina.
Wei-Chun ChenDepartment of Microbiology, Biochemistry and Molecular Genetics, Rutgers New Jersey Medical School, Newark, NJ 07103.
Dinghai ZhengDepartment of Microbiology, Biochemistry and Molecular Genetics, Rutgers New Jersey Medical School, Newark, NJ 07103.
Ezequiel PetrilloUniversidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Departamento de Fisiología, Biología Molecular y Celular and CONICET-UBA, Instituto de Fisiología, Biología Molecular y Neurociencias, Buenos Aires 1428, Argentina.ORCID 0000-0002-0025-3708
Bin TianDepartment of Microbiology, Biochemistry and Molecular Genetics, Rutgers New Jersey Medical School, Newark, NJ 07103.ORCID 0000-0001-8903-8256
Alberto R KornblihttUniversidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Departamento de Fisiología, Biología Molecular y Celular and CONICET-UBA, Instituto de Fisiología, Biología Molecular y Neurociencias, Buenos Aires 1428, Argentina.ORCID 0000-0003-4322-0831

Funding

Regulation of Alternative Cleavage and PolyadenylationR01GM084089 · NIGMS · WISTAR INSTITUTE · PI TIAN, BIN · 2008 to 2023
$6.7M
Regulation of gene expression by alternative polyadenylationR35GM153277 · NIGMS · WISTAR INSTITUTE · PI BIN TIAN · 2024 to 2026
$2.0M
Regulation and Functions of 3'UTRs in Cellular StressR01GM129069 · NIGMS · WISTAR INSTITUTE · PI TIAN, BIN · 2018 to 2021
$1.5M
Agencia Nacional de Promoción de la Investigación, el Desarrollo Tecnológico y la Innovación (Agencia I + D + i) PICT-2019-862HHS | NIH | National Institute of General Medical Sciences (NIGMS) GM084089HHS | NIH | National Institute of General Medical Sciences (NIGMS) GM129069NIGMS NIH HHS R01 GM084089NIGMS NIH HHS R01 GM129069NIGMS NIH HHS R35 GM153277UBA | Secretaría de Ciencia y Técnica, Universidad de Buenos Aires (UBACyT) UBACYT 20020170100046BA
6 · The paper itself

Abstract

Transcription of eukaryotic protein-coding genes generates immature mRNAs that are subjected to a series of processing events, including capping, splicing, cleavage, and polyadenylation (CPA), and chemical modifications of bases. Alternative polyadenylation (APA) greatly contributes to mRNA diversity in the cell. By determining the length of the 3' untranslated region, APA generates transcripts with different regulatory elements, such as miRNA and RBP binding sites, which can influence mRNA stability, turnover, and translation. In the model plant

Indexed as

ArabidopsisChloroplastsGene Expression Regulation, PlantLightPolyadenylationAlternative SplicingArabidopsis ProteinsRNA, MessengerArabidopsis ProteinsRNA, Messengeralternative polyadenylationArabidopsis thalianalight control in plants

Identifiers

PMID39150783
PMCPMC11348263

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.