ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2024
Allowing ad libitum sleep during overnight polysomnography affects Multiple Sleep Latency Test results in patients being assessed for hypersomnolence.
Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
STUDY
objectivesThe Multiple Sleep Latency Test (MSLT) is a key diagnostic component in the diagnosis of central disorders of hypersomnolence. Due to time constraints, it is common practice to wake patients at a standard time from overnight polysomnography (PSG) prior to the MSLT. This has the potential to influence MSLT results due to sleep deprivation. We describe the impact of allowing ad libitum sleep on the night prior to the MSLT in patients being assessed for hypersomnolence.
methodsA total of 580 consecutive patients undergoing PSG/MSLT for assessment of hypersomnolence were analyzed: 290 either side of a change in laboratory protocol that allowed patients ad libitum sleep during the PSG, rather than being woken at a prespecified time. Baseline characteristics, PSG and MSLT results were compared between the groups.
resultsGroups were similar at baseline, other than there being more females in the ad libitum group. After adjusting for confounding variables, patients allowed ad libitum sleep had later sleep offset time (+58.7 minutes;
conclusionsThe common practice of waking patients from their PSG at a standard time has the potential to curtail sleep and affect MSLT results by reducing mean sleep latency. Patients being assessed for hypersomnolence should be allowed ad libitum sleep during the PSG on the night prior to their MSLT. CITATION: Frenkel S, Amaranayake A, Molesworth C, Orellana L, Southcott AM. Allowing ad libitum sleep during overnight polysomnography affects Multiple Sleep Latency Test results in patients being assessed for hypersomnolence.
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