Evidence map›Paper›PMID 39150630›Full record

ArticleJournal of veterinary internal medicine

Parasympathetic tone activity, heart rate, and grimace scale in conscious horses of 3 breeds before, during, and after nociceptive mechanical stimulation.

Jorge Eduardo Mendoza Flores, Angelica Terrazas, Alma V Lara Sagahon, Monica Aleman

Abstract read
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jorge Eduardo Mendoza FloresDepartment of Livestock Sciences, Faculty of Higher Studies, Cuautitlan, National Autonomous University of Mexico (UNAM), Mexico City, Mexico.
Angelica TerrazasDepartment of Livestock Sciences, Faculty of Higher Studies, Cuautitlan, National Autonomous University of Mexico (UNAM), Mexico City, Mexico.
Alma V Lara SagahonDepartment of Livestock Sciences, Faculty of Higher Studies, Cuautitlan, National Autonomous University of Mexico (UNAM), Mexico City, Mexico.
Monica AlemanDepartment of Medicine and Epidemiology, School of Veterinary Medicine, University of California Davis, Davis, California, USA.ORCID https://orcid.org/0000-0001-5811-9520

Funding

Equine and Comparative Neurology Research Group V435AM2UNAM-DGAPA-PAPIIT IN224220 FESC-UNAM-CI2245
6 · The paper itself

Abstract

backgroundParasympathetic tone activity (PTA) in response to nociceptive stimulus in conscious non-sedated horses is unknown.

objectivesStudy PTA, heart rate (HR), and horse grimace scale (HGS) at rest and during mechanical nociceptive stimulation. ANIMALS: Ninety healthy young adult horses (females, males): 30 each of Friesians, Quarter Horses, and Warmbloods.

methodsProspective control study. The study consisted of habituation to equipment (Day 1), baseline recordings (Days 2 and 3), and nociceptive testing applying mild pressure to the metacarpus (Day 4). Parasympathetic tone, HR, and HGS were recorded simultaneously on Days 2 to 4. Each study lasted 30 minutes and was done in triplicate at 3 different time points per day.

resultsBaseline PTA was not different among breeds. It decreased in Warmbloods and Quarter Horses during placement of the stimulus device without stimulation (P < .01). A significant decrease in PTA (P < .001) occurred during nociceptive stimulus (marked in Quarter Horses, intermediate in Warmbloods, and mild in Friesians). Heart rate and HGS increased significantly (P < .001) during the stimulus in all breeds but returned to baseline poststimulation. Friesians required higher pressure (P < .05) to elicit an aversive response to the stimulus.

conclusionsHorses' PTA, HR, and HGS change in response to a mild mechanical nociceptive stimulus with Friesians showing less variation. Stress induced a decrease in PTA in Quarter Horses and Warmbloods but not in Friesians. Friesians appeared to be more tolerant to pain based on PTA, HR, and HGS findings compared with other breeds.

Indexed as

Heart RateAnimalsFemaleHorsesMaleNociceptionPain MeasurementParasympathetic Nervous SystemPhysical StimulationProspective Studiesautonomousbehaviorpainvagal tonewelfare

Identifiers

PMID39150630
PMCPMC11423482

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.