Evidence map›Paper›PMID 39150603›Full record

ArticleOphthalmology and therapy2024

Long-Term Impacts of Intense Pulsed Light Therapy on Ocular Surface Health and Tear Film Dynamics in Patients with Dry Eye Disease: Detailed Analysis and Observations Over a 1-Year Follow-Up Period.

Cristina-Patricia Pac, Mihnea Munteanu, José-María Sánchez-González, Carlos Rocha-de-Lossada, Nadina Mercea, Francis Ferrari, Horia T Stanca, Dan Andrei Radu Cosnita, Mihaela Ionica, Ovidiu Boruga and 2 more

Abstract read
In one paragraph

Article in Ophthalmology and therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Review
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Cristina-Patricia PacDepartment of Ophthalmology, "Victor Babes" University of Medicine and Pharmacy, 300041, Timisoara, Romania.
Mihnea MunteanuDepartment of Ophthalmology, "Victor Babes" University of Medicine and Pharmacy, 300041, Timisoara, Romania.
José-María Sánchez-GonzálezDepartment of Physics of Condensed Matter, Optics Area, University of Seville, Reina Mercedes Street, 41012, Seville, Spain. jsanchez80@us.es.ORCID http://orcid.org/0000-0003-0450-7717
Carlos Rocha-de-LossadaDepartment of Ophthalmology, Qvision VITHAS Almeria Hospital, 04120, Almeria, Spain.
Nadina MerceaDepartment of Ophthalmology, Municipal Clinical Emergency Hospital, 300254, Timisoara, Romania.
Francis FerrariClinique Espace Nouvelle Vision, 6 Rue de la Grande Chaumière, 75006, Paris, France.
Horia T StancaDepartment of Ophthalmology, "Carol Davila" University of Medicine and Pharmacy, 050474, Bucharest, Romania.
Dan Andrei Radu CosnitaDepartment of Ophthalmology, "Victor Babes" University of Medicine and Pharmacy, 300041, Timisoara, Romania.
Mihaela IonicaDepartment of Ophthalmology, "Victor Babes" University of Medicine and Pharmacy, 300041, Timisoara, Romania.
Ovidiu BorugaDepartment of Ophthalmology, "Victor Babes" University of Medicine and Pharmacy, 300041, Timisoara, Romania.
Ciprian DanielescuDepartment of Ophthalmology, "Grigore T Popa" University of Medicine and Pharmacy, 700115, Iasi, Romania.
Alexandru BlidiselDepartment of Ophthalmology, "Victor Babes" University of Medicine and Pharmacy, 300041, Timisoara, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTo evaluate the long-term effects of intense pulsed light (IPL) therapy on patients with dry eye disease (DED) associated with meibomian gland dysfunction (MGD).

methodsA retrospective case series was performed with 110 participants undergoing IPL therapy. Assessments included the eye fitness test (EFT) to gauge subjective symptoms, along with objective measures using the Tearcheck

resultsThis study documented significant improvements in subjective and objective symptoms associated with DED and MGD. Subjective symptoms measured by the EFT showed an average increase of 9.74 points (range -10 to 28, standard deviation [SD] ± 7.54), indicating reduced symptoms. Objective measures of tear film stability, represented by NIABUT, increased by an average of 4.04 s (range -15.00 to 14.40, SD ± 4.91). Tear film stability evaluation (TFSE) scores decreased by 229.12 points on average (range -1775 to 528, SD ± 384.94), suggesting enhanced tear film stability. OSIE type 1 showed a reduction in inflammation, with a percentage decrease of 4.98% (range -45 to 5, SD ± 7.33). Additionally, OSIE capture time decreased by 3.25 s on average (range -27 to 22, SD ± 10.35), further indicating an improvement in ocular surface health.

conclusionIPL therapy was shown to be a promising, noninvasive approach for improving quality of life in patients with DED by effectively managing symptoms and stabilizing tear film. The findings support the use of IPL as a sustainable treatment modality for DED associated with MGD.

Indexed as

Dry eye diseaseIntense pulsed light therapyLongitudinal studyMeibomian gland dysfunctionOcular surface healthTear film stability

Identifiers

PMID39150603
PMCPMC11408466

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.