Evidence map›Paper›PMID 39150229›Full record

ArticleACS synthetic biology2024

Desiccated Cyanobacteria Serve As Efficient Plasmid DNA Carriers in Space Flight.

Anne Kakouridis, Spencer Diamond, Thomas Eng, Heath J Mills, Olivia Gámez Holzhaus, Michael L Summers, Ferran Garcia-Pichel, Aindrila Mukhopadhyay

Abstract read
In one paragraph

Article in ACS synthetic biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anne KakouridisBiological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States.
Spencer DiamondInnovative Genomics Institute, University of California, Berkeley, California 94720, United States.
Thomas EngBiological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States.
Heath J MillsRhodium Scientific, Houston, Texas 77058, United States.
Olivia Gámez HolzhausRhodium Scientific, Houston, Texas 77058, United States.
Michael L SummersDepartment of Biology, California State University, Northridge, California 91330, United States.
Ferran Garcia-PichelSchool of Life Sciences, Arizona State University, Tempe, Arizona 85281, United States.ORCID 0000-0002-4974-3863
Aindrila MukhopadhyayBiological Systems and Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States.ORCID 0000-0002-6513-7425

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Effective transport of biological systems as cargo during space travel is a critical requirement to use synthetic biology and biomanufacturing in outer space. Bioproduction using microbes will drive the extent to which many human needs can be met in environments with limited resources. Vast repositories of biological parts and strains are available to meet this need, but their on-site availability requires effective transport. Here, we explore an approach that allows DNA plasmids, ubiquitous synthetic biology parts, to be safely transported to the International Space Station and back to the Kennedy Space Center without low-temperature or cryogenic stowage. Our approach relied on the cyanobacterium

Indexed as

Escherichia coliPlasmidsSpace FlightDesiccationKanamycin ResistanceNostocSynthetic BiologyCyanobacteriaInternational Space StationNostoc punctiformeSpace FlightSpace Travel

Identifiers

PMID39150229
PMCPMC11421212

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.