Evidence map›Paper›PMID 39150063›Full record

ArticleProtein science : a publication of the Protein Society2024

Profiling of coronaviral M

Wioletta Rut, Katarzyna Groborz, Xinyuanyuan Sun, Rolf Hilgenfeld, Marcin Drag

Abstract read
In one paragraph

Article in Protein science : a publication of the Protein Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Profiling of coronaviral MProtein science : a publication of the Protein Society · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wioletta RutDepartment of Chemical Biology and Bioimaging, Wroclaw University of Science and Technology, Wroclaw, Poland.
Katarzyna GroborzDepartment of Chemical Biology and Bioimaging, Wroclaw University of Science and Technology, Wroclaw, Poland.
Xinyuanyuan SunInstitute of Molecular Medicine, University of Lübeck, Lübeck, Germany.
Rolf HilgenfeldInstitute of Molecular Medicine, University of Lübeck, Lübeck, Germany.
Marcin DragDepartment of Chemical Biology and Bioimaging, Wroclaw University of Science and Technology, Wroclaw, Poland.ORCID 0000-0001-8510-1967

Funding

Fundacja na rzecz Nauki Polskiej
6 · The paper itself

Abstract

The main protease from coronaviruses and the 3C protease from enteroviruses play a crucial role in processing viral polyproteins, making them attractive targets for the development of antiviral agents. In this study, we employed a combinatorial chemistry approach-HyCoSuL-to compare the substrate specificity profiles of the main and 3C proteases from alphacoronaviruses, betacoronaviruses, and enteroviruses. The obtained data demonstrate that coronavirus M

Indexed as

Antiviral AgentsCoronavirus 3C ProteasesEnterovirusSARS-CoV-2CoronavirusHumansSubstrate SpecificityAntiviral AgentsCoronavirus 3C Proteasescoronavirusesenterovirusessubstrate specificityviral proteases

Identifiers

PMID39150063
PMCPMC11328108

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.