Evidence map›Paper›PMID 39149792›Full record

ArticleJournal of the Pediatric Infectious Diseases Society2024

Post-Artesunate Delayed Hemolysis in Pediatric Malaria Patients in the United States.

Sesh A Sundararaman, Karen L Hanze Villavicencio, Brianne Roper, Ziyi Wang, Amy K F Davis, Jonathan A Mayhew, Michelle L Wang, Nina L Tang, Vijaya L Soma, Gail F Shust and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the Pediatric Infectious Diseases Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Sesh A SundararamanDepartment of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.ORCID 0000-0001-9875-8378
Karen L Hanze VillavicencioDepartment of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Brianne RoperDepartment of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Ziyi WangDepartment of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Amy K F DavisDepartment of Pediatrics at UCSF, San Francisco, California, USA.
Jonathan A MayhewDepartment of Pediatric and Adolescent Medicine, Western Michigan University School of Medicine, Kalamazoo, Michigan, USA.
Michelle L WangDepartment of Pediatrics, Univeristy of Washington School of Medicine, Seattle, Washington, USA.
Nina L TangDepartment of Pediatrics, Baylor College of Medicine, Houston, Texas, USA.
Vijaya L SomaDepartment of Pediatrics, NYU Grossman School of Medicine, New York, New York City, USA.
Gail F ShustDepartment of Pediatrics, NYU Grossman School of Medicine, New York, New York City, USA.
Margaret E FeeneyDepartment of Pediatrics at UCSF, San Francisco, California, USA.
Indi TrehanDepartment of Pediatrics, Univeristy of Washington School of Medicine, Seattle, Washington, USA.
Jill E WeatherheadDepartment of Pediatrics, Baylor College of Medicine, Houston, Texas, USA.
Chandy C JohnDepartment of Pediatrics, Indiana University School of Medicine and Riley Hospital for Children, Indianapolis, Indiana, USA.ORCID 0000-0002-1634-1411
Jeffrey S GerberDepartment of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-3076-3186
Audrey R Odom JohnDepartment of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

Funding

MEP pathway resistance in Plasmodium falciparumR01AI103280 · NIAID · WASHINGTON UNIVERSITY · PI Audrey Ragan Odom John · 2013 to 2026
$5.5M
Combined Adult and Pediatric Infectious Disease Postdoctoral Training GrantT32AI118684 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI Rahul Manu Kohli, Audrey Ragan Odom John · 2016 to 2026
$2.3M
Mentoring Translational Researchers for Careers in Pediatric Global HealthK24AI113002 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FEENEY, MARGARET E · 2014 to 2023
$1.9M
NIAID NIH HHS K24 AI113002NIAID NIH HHS R01 AI103280NIAID NIH HHS T32 AI118684
6 · The paper itself

Abstract

Post-artesunate delayed hemolysis (PADH) occurred in 6 of 24 children treated with artesunate for severe malaria in the United States; however, severe hemolysis requiring hospitalization or transfusion was rare. In children in the United States treated with artesunate, counseling, and symptom monitoring may be preferred to weekly laboratory surveillance for PADH.

Indexed as

AntimalarialsArtesunateHemolysisChildChild, PreschoolFemaleHumansInfantMalariaMaleUnited StatesAntimalarialsArtesunateadverse drug reactionartesunatehemolytic anemiamalariapediatricpost-artesunate delayed hemolysis

Identifiers

PMID39149792
PMCPMC12106274

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.