Evidence map›Paper›PMID 39149510›Full record

SynthesisF1000Research2024

Osseointegrative and antimicrobial properties of graphene oxide nano coated dental implants: A systematic review.

Sounyala Rayannavar, Sunil Kumar Mv, Vignesh Kamath, Mahantesh Bembalgi, Namratha Nayak, Praveen Jodalli

Abstract readSystematic Review
In one paragraph

Synthesis in F1000Research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Graphene in dentistry: transformative applications and innovations.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sounyala RayannavarDepartment of Prosthodontics, KAHER's KLE Vishwanath Katti Institute of Dental Sciences, Belgavi, Karnataka, India.
Sunil Kumar MvDepartment of Prosthodontics, Jaipur Dental College, Maharaj Vinayak Global University, Jaipur, Rajasthan, India.
Vignesh KamathDepartment of Prosthodontics Crown and Bridge, Manipal college of Dental Sciences, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.ORCID https://orcid.org/0000-0002-4996-448X
Mahantesh BembalgiDepartment of Prosthodontics, KAHER's KLE Vishwanath Katti Institute of Dental Sciences, Belgavi, Karnataka, India.
Namratha NayakDepartment of Periodontology, Manipal College of Dental Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.
Praveen JodalliDepartment of Public Health Dentistry, Manipal College of Dental Sciences, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, 575001, India.ORCID https://orcid.org/0000-0002-6243-9823

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Osseointegration stands as a pivotal concept within the realm of dental implants, signifying the intricate process through which a dental implant integrates with the adjoining bone tissue. Graphene oxide (GO) has been shown to promote osseointegration, the process by which the implant fuses with the surrounding bone. The objective of this study was to assess the osseointegrative and antimicrobial properties of GO nano coated dental implants. Methods: A systematic search was conducted using electronic databases (e.g., PubMed, Scopus, Web of Science) to identify relevant studies published. Inclusion criteria encompassed studies that evaluated the effects of GO nano coating on osseointegrative and antimicrobial characteristics of dental implants. Studies not written in English and published before 2012 were excluded. Results: The initial search yielded a total of 127 potential studies, of which six met the inclusion criteria and five were included in the review. These studies provided data on GO nano coated dental implants and their osseointegrative and antimicrobial properties. All the included studies showed moderate risk of bias. None of the studies provided information related to sample size calculation or sampling technique. Discussion: The findings from the included studies demonstrated that GO nano coating had a positive impact on osseointegrative properties of dental implants. Enhanced bone-implant contact and increased bone density were observed in animals and humans receiving GO nano coated implants. Furthermore, the antimicrobial properties of GO nano coating were found to inhibit bacterial colonization and biofilm formation on the implant surface, reducing the risk of implant-associated infections. Conclusion: The findings indicate that GO nano coating holds promise in enhancing the success rate and longevity of dental implants. However, more studies with larger sample sizes, are needed to further strengthen the evidence and determine the long-term effects of GO nano coated dental implants.

Indexed as

Anti-Infective AgentsCoated Materials, BiocompatibleDental ImplantsGraphiteOsseointegrationAnimalsHumansNanostructuresAnti-Infective AgentsCoated Materials, BiocompatibleDental Implantsgraphene oxideGraphiteantimicrobial propertiesdental implantsGraphene oxideosseointegrationsystematic review

Identifiers

PMID39149510
PMCPMC11325139

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.