Evidence map›Paper›PMID 39149491›Full record

ArticleResearch square2024

Comparative physiology and morphology of BLA-projecting NBM/SI cholinergic neurons in mouse and macaque.

Feng Luo, Li Jiang, Niraj S Desai, Li Bai, Gabrielle V Watkins, Mark A G Eldridge, Anya Plotnikova, Arya Mohanty, Alex C Cummins, Bruno B Averbeck and 2 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Feng LuoSection on Circuits, Synapses, and Molecular Signaling, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, 20892, MD, USA.
Li JiangSection on Genetics of Neuronal Signaling, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, 20892, MD, USA.
Niraj S DesaiSection on Circuits, Synapses, and Molecular Signaling, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, 20892, MD, USA.
Li BaiSection on Circuits, Synapses, and Molecular Signaling, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, 20892, MD, USA.
Gabrielle V WatkinsSection on Circuits, Synapses, and Molecular Signaling, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, 20892, MD, USA.
Mark A G EldridgeLaboratory of Neuropsychology, National Institute of Mental Health, Bethesda, 20892, MD, USA.
Anya PlotnikovaLaboratory of Neuropsychology, National Institute of Mental Health, Bethesda, 20892, MD, USA.
Arya MohantyLaboratory of Neuropsychology, National Institute of Mental Health, Bethesda, 20892, MD, USA.
Alex C CumminsLaboratory of Neuropsychology, National Institute of Mental Health, Bethesda, 20892, MD, USA.
Bruno B AverbeckLaboratory of Neuropsychology, National Institute of Mental Health, Bethesda, 20892, MD, USA.
David A TalmageSection on Genetics of Neuronal Signaling, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, 20892, MD, USA.
Lorna W RoleSection on Circuits, Synapses, and Molecular Signaling, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, 20892, MD, USA.

Funding

Frontal Striatal Systems and Dopamine in Normal and Pathological BehaviorZIAMH002928 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI AVERBECK, BRUNO · 2010 to 2025
$29.0M
Intramural NIH HHS ZIA MH002928
6 · The paper itself

Abstract

Cholinergic projection neurons of the nucleus basalis and substantia innominata (NBM/SI) densely innervate the basolateral amygdala (BLA) and have been shown to contribute to the encoding of fundamental and life-threatening experiences. Given the vital importance of these circuits in the acquisition and retention of memories that are essential for survival in a changing environment, it is not surprising that the basic anatomical organization of the NBM/SI is well conserved across animal classes as diverse as teleost and mammal. What is not known is the extent to which the physiology and morphology of NBM/SI neurons have also been conserved. To address this issue, we made patch-clamp recordings from NBM/SI neurons in

Indexed as

basal forebraincholinergicmorpho-electric physiologymousenonhuman primate

Identifiers

PMID39149491
PMCPMC11326416

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.