Evidence map›Paper›PMID 39149417›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering

Studies of DNA breathing in exciton-coupled (iCy3)

Jack Maurer, Claire S Albrecht, Patrick Herbert, Dylan Heussman, Anabel Chang, Peter H von Hippel, Andrew H Marcus

Abstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jack MaurerCenter for Optical, Molecular and Quantum Science, Department of Chemistry and Biochemistry, University of Oregon, Eugene, Oregon 97403.
Claire S AlbrechtCenter for Optical, Molecular and Quantum Science, Department of Chemistry and Biochemistry, University of Oregon, Eugene, Oregon 97403.
Patrick HerbertCenter for Optical, Molecular and Quantum Science, Department of Chemistry and Biochemistry, University of Oregon, Eugene, Oregon 97403.
Dylan HeussmanCenter for Optical, Molecular and Quantum Science, Department of Chemistry and Biochemistry, University of Oregon, Eugene, Oregon 97403.
Anabel ChangInstitute of Molecular Biology, Department of Chemistry and Biochemistry, and University of Oregon, Eugene, Oregon 97403.
Peter H von HippelInstitute of Molecular Biology, Department of Chemistry and Biochemistry, and University of Oregon, Eugene, Oregon 97403.
Andrew H MarcusCenter for Optical, Molecular and Quantum Science, Department of Chemistry and Biochemistry, University of Oregon, Eugene, Oregon 97403.

Funding

STRUCTURE AND RELATIONS OF PROTEINS AND NUCLEIC ACIDSR01GM015792 · NIGMS · UNIVERSITY OF OREGON · PI MARCUS, ANDREW HADLEY · 1985 to 2025
$10.2M
NIGMS NIH HHS R01 GM015792
6 · The paper itself

Abstract

Local fluctuations of the sugar-phosphate backbones and bases of DNA (a form of DNA 'breathing') play a central role in the assembly of protein-DNA complexes. We present a single-molecule fluorescence method to sensitively measure the local conformational fluctuations of exciton-coupled cyanine [(iCy3)

Indexed as

DNA ‘breathing,’ Protein-DNA interactionsExciton-coupled dimer probe-labeled DNAFree energy surfacePhase-tagged photon-counting (PTPC)Polarization-selective single-molecule fluorescence imagingSingle-molecule optical microscopy

Identifiers

PMID39149417
PMCPMC11326516

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.