Evidence map›Paper›PMID 39149397›Full record

ArticlebioRxiv : the preprint server for biology2024

Cysteine depletion triggers adipose tissue thermogenesis and weight-loss.

Aileen H Lee, Lucie Orliaguet, Yun-Hee Youm, Rae Maeda, Tamara Dlugos, Yuanjiu Lei, Daniel Coman, Irina Shchukina, Sairam Andhey, Steven R Smith and 6 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors.

Aileen H LeeDepartment of Pathology, Yale School of Medicine, New Haven, CT 06520, USA.
Lucie OrliaguetDepartment of Pathology, Yale School of Medicine, New Haven, CT 06520, USA.
Yun-Hee YoumDepartment of Pathology, Yale School of Medicine, New Haven, CT 06520, USA.
Rae MaedaUniversity of Kyoto, Japan.
Tamara DlugosDepartment of Pathology, Yale School of Medicine, New Haven, CT 06520, USA.
Yuanjiu LeiDepartment of Pathology, Yale School of Medicine, New Haven, CT 06520, USA.
Daniel ComanDepartment of Radiology and Biomedical Imaging, School of Engineering and Applied Science, Yale University.
Irina ShchukinaDepartment of Pathology and Immunology Washington University School of Medicine, St. Louis, MO 63110, USA.
Sairam AndheyDepartment of Pathology and Immunology Washington University School of Medicine, St. Louis, MO 63110, USA.
Steven R SmithTranslational Research Institute for Metabolism and Diabetes, AdventHealth, Orlando, FL, USA.
Eric RavussinPennington Biomedical Research Center, Baton Rouge, LA, USA.
Krisztian StadlerPennington Biomedical Research Center, Baton Rouge, LA, USA.
Fahmeed HyderDepartment of Radiology and Biomedical Imaging, School of Engineering and Applied Science, Yale University.
Maxim N ArtyomovDepartment of Pathology and Immunology Washington University School of Medicine, St. Louis, MO 63110, USA.
Yuki SugiuraUniversity of Kyoto, Japan.
Vishwa Deep DixitDepartment of Pathology, Yale School of Medicine, New Haven, CT 06520, USA.

Funding

The role of AgRP/Auga-ALK pathway in FGF21's brain action on agingP01AG051459 · NIA · YALE UNIVERSITY · PI VISHWA DEEP DIXIT · 2016 to 2026
$25.7M
UT Southwestern NORCP30DK127984 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI Jeffrey M Zigman · 2022 to 2026
$7.4M
Caloric restriction-driven immunometabolic checkpoints of inflammationR01AG073969 · NIA · YALE UNIVERSITY · PI VISHWA DEEP DIXIT · 2022 to 2026
$2.5M
Impact of dysbiosis on the development of age-related inflammationR01AG068863 · NIA · YALE UNIVERSITY · PI DIXIT, VISHWA DEEP, PALM, NOAH WOLCOTT · 2020 to 2024
$2.2M
Impact of Calorie Restriction on Thymopoiesis in HumansR01AG031797 · NIA · YALE UNIVERSITY · PI DIXIT, VISHWA DEEP · 2008 to 2015
$1.2M
Novel redox mechanisms of oxygenated phospholipids in chronic and diabetic kidney diseaseR01DK137472 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI STADLER, KRISZTIAN · 2023 to 2025
$888k
NIA NIH HHS P01 AG051459NIA NIH HHS R01 AG031797NIA NIH HHS R01 AG068863NIA NIH HHS R01 AG073969NIDDK NIH HHS P30 DK127984NIDDK NIH HHS R01 DK137472
6 · The paper itself

Abstract

Dietary interventions such as caloric restriction (CR)

Identifiers

PMID39149397
PMCPMC11326254

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.