Evidence map›Paper›PMID 39149373›Full record

ArticlebioRxiv : the preprint server for biology2024

Therapeutic

Noor Momin, Steffen Pabel, Arnab Rudra, Nina Kumowski, I-Hsiu Lee, Kyle Mentkowski, Masahiro Yamazoe, Laura Stengel, Charlotte G Muse, Hana Seung and 15 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

25 authors.

Noor MominCenter for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Steffen PabelCenter for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Arnab RudraDepartment of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Boston, MA, USA.
Nina KumowskiCenter for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
I-Hsiu LeeCenter for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Kyle MentkowskiCenter for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Masahiro YamazoeCenter for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Laura StengelDepartment of Internal Medicine II, University Medical Center Regensburg, Regensburg, Germany.
Charlotte G MuseCenter for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Hana SeungCenter for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Alexandre PaccaletCenter for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Cristina Gonzalez-CorreaCenter for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Emily B JacobsDepartment of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA.
Jana GruneCenter for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Maximilian J SchlossCenter for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Samuel SossallaDepartment of Cardiology, University Hospital Giessen, Kerckhoff Clinic Bad Nauheim, and DZHK, Partner site RhineMain, Germany.
Gregory WojtkiewiczCenter for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Yoshiko IwamotoCenter for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Patrick McMullenDepartment of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Boston, MA, USA.
Richard N MitchellDepartment of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
Patrick T EllinorCardiovascular Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-2067-0533
Daniel G AndersonDepartment of Anesthesiology, Critical Care and Pain Medicine, Boston Children's Hospital, Boston, MA, USA.
Kamila NaxerovaBlavatnik Institute, Genetics, Harvard Medical School, Boston, MA, USA.
Matthias NahrendorfCenter for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Maarten HulsmansCenter for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.ORCID 0000-0003-1009-658X

Funding

IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVALR01HL092577 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI BENJAMIN, EMELIA J., ELLINOR, PATRICK THOMAS · 2009 to 2025
$20.6M
PROJECT 4: Somatic evolution of the hematopoietic system in cardiovascular diseaseP01HL142494 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI Matthias Nahrendorf · 2019 to 2026
$19.5M
Training Grant in Molecular Imaging Research (MGH/HMS)T32CA079443 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI WEISSLEDER, MD, PHD, RALPH · 2000 to 2025
$10.1M
Imaging organ system interfaces in ischemic heart diseaseR35HL139598 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI NAHRENDORF, MATTHIAS · 2018 to 2024
$6.9M
Cardiac resident macrophages in AV node conductionR01HL149647 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI HULSMANS, MAARTEN · 2022 to 2025
$2.9M
Using Electrocardiogram Genetics to Inform Arrhythmia RiskR01HL157635 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI ELLINOR, PATRICK THOMAS, MIRSHAHI, TOORAJ · 2022 to 2025
$2.9M
Macrophage heterogeneity in atrial remodelingR01HL155097 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI HULSMANS, MAARTEN · 2021 to 2025
$2.9M
Combinatorial and computational design of bnAb mRNA vaccines for HIVR61AI161805 · NIAID · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI ANDERSON, DANIEL G · 2021 to 2023
$2.1M
Combinatorial and computational design of bnAb mRNA vaccines for HIVR33AI161805 · NIAID · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI ANDERSON, DANIEL G · 2024 to 2025
$1.5M
NCI NIH HHS T32 CA079443NHLBI NIH HHS P01 HL142494NHLBI NIH HHS R01 HL092577NHLBI NIH HHS R01 HL149647NHLBI NIH HHS R01 HL155097NHLBI NIH HHS R01 HL157635NHLBI NIH HHS R35 HL139598NIAID NIH HHS R33 AI161805NIAID NIH HHS R61 AI161805
6 · The paper itself

Abstract

Atrial fibrillation (AFib) and the risk of its lethal complications are propelled by fibrosis, which induces electrical heterogeneity and gives rise to reentry circuits. Atrial TREM2

Identifiers

PMID39149373
PMCPMC11326243

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.