Evidence map›Paper›PMID 39149313›Full record

ArticlebioRxiv : the preprint server for biology2024

The synaptonemal complex aligns meiotic chromosomes by wetting.

Spencer G Gordon, Alyssa A Rodriguez, Yajie Gu, Kevin D Corbett, Chiu Fan Lee, Ofer Rog

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Spencer G GordonSchool of Biological Sciences and Center for Cell and Genome Sciences, University of Utah, United States.
Alyssa A RodriguezDepartment of Cellular and Molecular Medicine, University of California San Diego, La Jolla CA 92093.
Yajie GuDepartment of Cellular and Molecular Medicine, University of California San Diego, La Jolla CA 92093.
Kevin D CorbettDepartment of Cellular and Molecular Medicine, University of California San Diego, La Jolla CA 92093.
Chiu Fan LeeDepartment of Bioengineering, Imperial College London, United Kingdom.ORCID 0000-0003-4363-9050
Ofer RogSchool of Biological Sciences and Center for Cell and Genome Sciences, University of Utah, United States.ORCID 0000-0001-6558-6194

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
Structure and dynamics of meiotic chromosomesR35GM128804 · NIGMS · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Ofer Rog · 2018 to 2026
$4.1M
Molecular mechanisms of nucleic acid recognition and maintenance in meiosis and innate immunityR35GM144121 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Kevin Daniel Corbett · 2022 to 2026
$2.7M
NIGMS NIH HHS R35 GM128804NIGMS NIH HHS R35 GM144121NIH HHS P40 OD010440
6 · The paper itself

Abstract

During meiosis, the parental chromosomes are drawn together to enable exchange of genetic information. Chromosomes are aligned through the assembly of a conserved interface, the synaptonemal complex, composed of a central region that forms between two parallel chromosomal backbones called axes. Here we identify the axis-central region interface in

Indexed as

C. eleganscondensationHORMAmeiosissynaptonemal complexwetting

Identifiers

PMID39149313
PMCPMC11326210

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.