Evidence map›Paper›PMID 39149244›Full record

ArticlebioRxiv : the preprint server for biology2024

Spatial localization of CD16a at the human NK cell ADCC lytic synapse.

Patrick Ross, Hijab Fatima, Dan P Leaman, Jessica Matthias, Kathryn Spencer, Michael B Zwick, Scott C Henderson, Emily M Mace, Charles Daniel Murin

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Patrick RossSan Diego Biomedical Research Institute, San Diego, CA, USA.ORCID 0000-0003-1264-2273
Hijab FatimaDepartment of Pediatrics, Columbia University Irving Medical Center, New York, NY, USA.
Dan P LeamanDepartment of Immunology and Microbiology, Scripps Research, La Jolla, CA, USA.
Jessica MatthiasAbberior Instruments America, Bethesda, MD, USA.
Kathryn SpencerCore Microscopy Facility, Scripps Research, La Jolla, CA, USA.
Michael B ZwickDepartment of Immunology and Microbiology, Scripps Research, La Jolla, CA, USA.ORCID 0000-0002-0885-2502
Scott C HendersonCore Microscopy Facility, Scripps Research, La Jolla, CA, USA.ORCID 0000-0002-1076-3867
Emily M MaceDepartment of Pediatrics, Columbia University Irving Medical Center, New York, NY, USA.ORCID 0000-0003-0226-7393
Charles Daniel MurinSan Diego Biomedical Research Institute, San Diego, CA, USA.ORCID 0000-0002-1610-9276

Funding

Combining membrane Env vaccine regimens to elicit multiple bnAb lineages and consistent cross-neutralization of HIVR01AI181784 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI Laurent Karl Verkoczy, MICHAEL B ZWICK · 2024 to 2026
$2.8M
HIV antibodies and NK cell ADCC: nanometer-scale tracking of immune synapse dynamics.R01AI167646 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI MURIN, CHARLES DANIEL · 2021 to 2025
$2.5M
NIAID NIH HHS R01 AI167646NIAID NIH HHS R01 AI181784
6 · The paper itself

Abstract

Natural Killer (NK) cells utilize effector functions, including antibody-dependent cellular cytotoxicity (ADCC), for the clearance of viral infection and cellular malignancies. NK cell ADCC is mediated by Fc

Identifiers

PMID39149244
PMCPMC11326286

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.