Evidence map›Paper›PMID 39149146›Full record

ArticleInternational Symposium on String Processing and Information Retrieval : SPIRE ... : proceedings. SPIRE (Symposium)2023

Data Structures for SMEM-Finding in the PBWT.

Paola Bonizzoni, Christina Boucher, Davide Cozzi, Travis Gagie, Dominik Köppl, Massimiliano Rossi

Abstract read
In one paragraph

Article in International Symposium on String Processing and Information Retrieval : SPIRE ... : proceedings. SPIRE (Symposium), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Haplotype Matching with GBWT for Pangenome Graphs.bioRxiv : the preprint server for biology · 2025
    Article
  2. An Efficient Data Structure and Algorithm for Long-Match Query in Run-Length Compressed BWT.Algorithms in bioinformatics : ... International Workshop, WABI ..., proceedings. WABI (Workshop) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Paola BonizzoniUniversity of Milano-Bicocca, Milano, Italy.ORCID 0000-0001-7289-4988
Christina BoucherUniversity of Florida, Gainesville, FL.ORCID 0000-0001-9509-9725
Davide CozziUniversity of Milano-Bicocca, Milano, Italy.ORCID 0000-0003-2439-0608
Travis GagieDalhousie University, Halifax, NS, Canada.ORCID 0000-0003-3689-327X
Dominik KöpplUniversity of Muenster, Muenster, Germany.ORCID 0000-0002-8721-4444
Massimiliano RossiUniversity of Florida, Gainesville, FL.ORCID 0000-0002-3012-1394

Funding

Personal and panel references for improved alignmentR01HG011392 · NHGRI · JOHNS HOPKINS UNIVERSITY · PI LANGMEAD, BENJAMIN THOMAS · 2020 to 2025
$4.2M
NHGRI NIH HHS R01 HG011392
6 · The paper itself

Abstract

The positional Burrows-Wheeler Transform (PBWT) was presented as a means to find set-maximal exact matches (SMEMs) in haplotype data via the computation of the divergence array. Although run-length encoding the PBWT has been previously considered, storing the divergence array along with the PBWT in a compressed manner has not been as rigorously studied. We define two queries that can be used in combination to compute SMEMs, allowing us to define smaller data structures that support one or both of these queries. We combine these data structures, enabling the PBWT and the divergence array to be stored in a manner that allows for finding SMEMs. We estimate and compare the memory usage of these data structures, leading to one data structure that is most memory efficient. Lastly, we implement this data structure and compare its performance to prior methods using various datasets taken from the 1000 Genomes Project data.

Identifiers

PMID39149146
PMCPMC11325217

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.