Evidence map›Paper›PMID 39149126›Full record

ArticleGynecologic oncology reports2024

Secondary cytoreduction in recurrent ovarian cancer- experience from a tertiary care centre in India.

Priya Bhati, Anitha Thomas, Rachel George Chandy, Amrita Datta, Dhanya Susan Thomas, Vinotha Thomas, Abraham Peedicayil, Ajit Sebastian

Abstract read
In one paragraph

Article in Gynecologic oncology reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Priya BhatiDepartment of Gynaecologic Oncology, Christian Medical College, Vellore, Tamil Nadu, India.
Anitha ThomasDepartment of Gynaecologic Oncology, Christian Medical College, Vellore, Tamil Nadu, India.
Rachel George ChandyDepartment of Gynaecologic Oncology, Christian Medical College, Vellore, Tamil Nadu, India.
Amrita DattaDepartment of Gynaecologic Oncology, Christian Medical College, Vellore, Tamil Nadu, India.
Dhanya Susan ThomasDepartment of Gynaecologic Oncology, Christian Medical College, Vellore, Tamil Nadu, India.
Vinotha ThomasDepartment of Gynaecologic Oncology, Christian Medical College, Vellore, Tamil Nadu, India.
Abraham PeedicayilDepartment of Gynaecologic Oncology, Christian Medical College, Vellore, Tamil Nadu, India.
Ajit SebastianDepartment of Gynaecologic Oncology, Christian Medical College, Vellore, Tamil Nadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Ovarian cancer is a disease that presents in advanced stage, due to the absence of any specific or overtly dramatic symptoms. The standard of care is primary debulking surgery, followed by chemotherapy. Ovarian cancer recurrence treatment is very challenging and there is always a debate between cytoreduction vs chemotherapy. Methods: The electronic medical records of all patients who underwent secondary cytoreductive surgery for recurrent ovarian cancer between January 2011 and December 2019 were retrieved the patients with platinum sensitive recurrent ovarian cancer who underwent secondary cytoreductive surgery in our department during this time period were included. Results: A total of 52 patients underwent secondary cytoreductive surgery for recurrent ovarian cancer during the study period. Median treatment free interval after primary treatment was 20 months (range 6-132). The secondary cytoreductive surgery was highly complex in 4(8 %) patients,19 (37 %) had intermediate surgical complexity score, 29 (55 %) had low surgical complexity score according to the Aletti complexity score. Secondary cytoreductive surgery was complete (no macroscopic residual disease) in 31(60 %); Optimal (R1) in 17 (33 %) and suboptimal in only 4 (7 %) of the patients. Out of the 52 patients,8 expired, 16 had a second recurrence, and 10 were lost to follow up over time. Conclusion: Successful surgery is possible in well selected patients, which in turn can lead to a meaningful progression free and overall survival benefit. Meticulous individualisation of cases should be done keeping in mind the patient's performance status, prior treatment history & toxicity; distribution & extent of disease, and the patient's overall life goals.

Indexed as

Ovarian cancer recurrenceSecondary cytoreductionSurvival outcome

Identifiers

PMID39149126
PMCPMC11325282

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