Evidence map›Paper›PMID 39149092›Full record

ArticleRSC medicinal chemistry2024

Responsive ZIF-90 nanocomposite material: targeted delivery of 10-hydroxycamptothecine to enhance the therapeutic effect of colon cancer (HCT116) cells.

Ji-Chao Guo, Shi-Hui Deng, Shu-Min Zhou, Xuan Zhou, Jiajia Du, Si-Han Zhou, Qi-Hua Zhao, Zhong-Yan Cai, Xiaoxia Ren, Ming-Jin Xie

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ji-Chao GuoSchool of Chemical Science and Technology, Yunnan University Kunming 650091 Yunnan China mjxie@ynu.edu.cn.
Shi-Hui DengSchool of Chemical Science and Technology, Yunnan University Kunming 650091 Yunnan China mjxie@ynu.edu.cn.
Shu-Min ZhouSchool of Chemical Science and Technology, Yunnan University Kunming 650091 Yunnan China mjxie@ynu.edu.cn.
Xuan ZhouSchool of Chemical Science and Technology, Yunnan University Kunming 650091 Yunnan China mjxie@ynu.edu.cn.ORCID https://orcid.org/0009-0008-6739-8232
Jiajia DuSchool of Chemical Science and Technology, Yunnan University Kunming 650091 Yunnan China mjxie@ynu.edu.cn.
Si-Han ZhouSchool of Chemical Science and Technology, Yunnan University Kunming 650091 Yunnan China mjxie@ynu.edu.cn.ORCID https://orcid.org/0000-0002-8840-6800
Qi-Hua ZhaoSchool of Chemical Science and Technology, Yunnan University Kunming 650091 Yunnan China mjxie@ynu.edu.cn.ORCID https://orcid.org/0000-0001-8165-1793
Zhong-Yan CaiSchool of Chemical Science and Technology, Yunnan University Kunming 650091 Yunnan China mjxie@ynu.edu.cn.
Xiaoxia RenAnimal Research and Resource Center, School of Life Sciences, Yunnan University Kunming 650091 Yunnan China.
Ming-Jin XieSchool of Chemical Science and Technology, Yunnan University Kunming 650091 Yunnan China mjxie@ynu.edu.cn.ORCID https://orcid.org/0000-0001-5675-4811

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is significant value in developing multifunctional drug delivery systems with high therapeutic efficiency for diagnosing and treating tumors. In this study, we synthesized the ATP-triggered and pH-sensitive material ZIF-90 using the liquid-phase diffusion method. This was done to load 10-hydroxycamptothecin (HCPT), and the FA-PEG-NH

Identifiers

PMID39149092
PMCPMC11324039

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.